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Congratulations to Dr. Shieh, Sheau-Yann for her promotion to Research Fellow on Feburary 1st, 2012. (
2012/02/08 ) |
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Professor Konan Peck passed away on December 22nd. Professor Peck's memorial service info is as follows:
Public Memorial Ceremony for Professor Konan Peck will be held on Saturday January 14, 2012 at 14:00pm at The Taipei Municipal Second Funeral Parlor.
IBMS Memorial Ceremony to honor Professor Konan Peck will be held on Thursday January 19, 2012 at 15:00pm at IBMS B1C Auditorium. (
2012/1/05 ) |
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Congratulations to Dr. Chen-Yang Shen for receiving the 21th "Wang Min-Ning Memorial Award" for Outstanding Contribution to the Development Medical Science and Technology, National Health and Society. (
2011/11/30 ) |
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Academician Cheng-Wen Wu has been awarded the 2011 Presidential Science Prize for his outstanding contribution of playing a leading role in the advancement of biomedical science. (
2011/11/18 ) |
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We welcome Dr. Reiji Kannagi, Visiting Professor of Aichi Medical University, Japan, to join our Institute as a Distinguished Research Fellow starting November 14th, 2011. (
2011/11/16 ) |
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A research team led by Dr. Chih-Cheng Chen, Institute of Biomedical Sciences, Academia Sinica has discovered a novel antinociceptive mechanism against acid-induced chronic muscle pain. (
2011/11/15 ) |
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2/20 (Monday) 11:00-12:00 Noon B1B Lecture Room, IBMS
Resolution of Sympathetic Rhythms.
Chun-Kuei Su, Ph.D. |
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| Conferences - - - - - - - - - - - - - - - - - - - - - - - - - - - more |
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Research Highlight - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - archive |
Dr. Eminy H. Y. Lee
J Neurosci., Feb 1st, 2012
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JNK1 Inhibits GluR1 Expression and GluR1-Mediated Calcium Influx through Phosphorylation and Stabilization of Hes-1.
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The GluR1 subunit of the AMPA receptor plays an important role in excitatory synaptic transmission and synaptic plasticity in the brain, but the regulation mechanism for GluR1 expression is largely unknown. Hairy and enhancer of split 1 (Hes-1) is a mammalian transcription repressor that regulates neuronal differentiation and development, but the role of Hes-1 in differentiated neurons is also less known. |
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Dr. Huang, Yi-Shuian
EMBO J, Dec 9, 2011
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CPEB2–eEF2 interaction impedes HIF-1α RNA translation
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Translation of mRNA into protein proceeds in three phases: initiation, elongation, and termination. Regulated translation allows the prompt production of selective proteins in response to physiological needs and is often controlled by sequence-specific RNA-binding proteins that function at initiation. Whether the elongation phase of translation can be modulated individually by trans-acting factors to synthesize polypeptides at variable rates remains to be determined |
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Dr. Cheng, Chin-Feng and Dr. Chen, Chih-Cheng
Pharmacol Ther., Dec 30, 2011
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Targeting ASIC3 for pain, anxiety, and insulin resistance.
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Acid-sensing ion channel 3 (ASIC3) is a sensitive pH sensor predominantly expressed in nociceptors and responds to mild extracellular acidification. Therefore, targeting ASIC3 as an analgesic for pain associated with tissue acidosis is of great interest. Selective drugs targeting ASIC3 have been effective in relieving acid-evoked pain in animal models and human studies. |
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Dr. Lim, Carmay
Nucl. Acids Res, Dec 1st, 2011
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GeoPCA: a new tool for multivariate analysis of dihedral angles based on principal component geodesics.
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The GeoPCA package is the first tool developed for multivariate analysis of dihedral angles based on principal component geodesics. Principal component geodesic analysis provides a natural generalization of principal component analysis for data distributed in non-Euclidean space, as in the case of angular data. GeoPCA presents projection of angular data on a sphere composed of the first two principal component geodesics, allowing clustering based on dihedral angles as opposed to Cartesian coordinates. |
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