2017

  1. Chia-Chen Lu呂佳臻 (Advisor: Dr. Woan-Yuh Tarn)
    Lu CC, Lee CC, Tseng CT, Tarn WY (2017) Y14 governs p53 expression and modulates DNA damage sensitivity. Sci Rep. 7:45558. doi: 10.1038/srep45558 [PDF]
  2. Jui-Hao Lee李睿豪 (Advisor: Dr. Chi-Hung Lin)
    Lee JH, Hsieh CF, Liu HW, Chen CY, Wu SC, Chen TW, Hsu CS, Liao YH, Yang CY, Shyu JF, Fischer WB, Lin CH (2017) Lipid raft-associated stomatin enhances cell fusion. FASEB J. 31(1):47-59. doi: 10.1096/fj.201600643R [PDF]

2016

  1. Pei-Yi Su 蘇倍儀 (Advisor: Dr. Chiaho Shih)
    Su PY, Yang CJ, Chu TH, Chang CH, Chiang C, Tang FM, Lee CY, Shih C (2016) HBV maintains electrostatic homeostasis by modulating negative charges from phosphoserine and encapsidated nucleic acids. Sci Rep. 6:38959. doi: 10.1038/srep38959 [PDF]
  2. Marilyn Rimando雷瑪琳 (Advisor: Dr. Oscar Kuang-Sheng Lee)
    Rimando MG, Wu HH, Liu YA, Lee CW, Kuo SW, Lo YP, Tseng KF, Liu YS, Lee OK (2016) Glucocorticoid receptor and Histone deacetylase 6 mediate the differential effect of dexamethasone during osteogenesis of mesenchymal stromal cells (MSCs). Sci Rep. 6:37371. doi: 10.1038/srep37371 [PDF]
  3. An-Ting Liou 劉安庭 (Advisor: Dr. Chiaho Shih)
    Liou AT, Wu SY, Liao CC, Chang YS, Chang CS, Shih C (2016) A new animal model containing human SCARB2 and lacking stat-1 is highly susceptible to EV71. Sci Rep. 6:31151. doi: 10.1038/srep31151 [PDF]
  4. Nana Hsiang-Hua Wang 王襄華 (Advisor: Dr. Yuan-Tsong Chen)
    Wang NH, Chen SJ, Yang CF, Chen HW, Chuang HP, Lu YH, Chen CH, Wu JY, Niu DM, Chen YT (2016) Homozygosity Mapping and Whole-Genome Sequencing Links a Missense Mutation in POMGNT1 to Autosomal Recessive Retinitis Pigmentosa. Invest Ophthalmol Vis Sci. 57(8):3601-9. doi: 10.1167/iovs.16-19463 [PDF]
  5. Tzu-Po Chuang 莊諮博 (Advisor: Dr. Yuan-Tsong Chen & Dr. Ling-Hui Li)
    Chuang TP, Wang JY, Jao SW, Wu CC, Chen JH, Hsiao KH, Lin CY, Chen SH, Su SY, Chen YJ, Chen YT, Wu DC, Li LH (2016) Over-expression of AURKA, SKA3 and DSN1 contributes to colorectal adenoma to carcinoma progression. Oncotarget. doi: 10.18632/oncotarget.9960 [PDF]
  6. Wei-Sheng Sun 孫維聲 (Advisor: Dr. Wan-Jr Syu)
    Sun WS, Chen JW, Wu YC, Tsai HY, Kuo YL, Syu WJ (2016) Expression Regulation of Polycistronic lee3 Genes of Enterohaemorrhagic Escherichia coli. PLoS One. 11(5):e0155578 [PDF]
  7. Ching-Pang Chang 張敬邦 (Advisor: Dr. Yijuang Chern)
    Chang CP, Lee CT, Hou WH, Lin MS, Lai HL, Chien CL, Chang C, Cheng PL, Lien CC, Chern Y (2016) Type VI adenylyl cyclase negatively regulates GluN2B-mediated LTD and spatial reversal learning. Sci Rep. 6:22529 [PDF]
  8. Pierre-Alain Burnouf 白宸睿 (Advisor: Dr. Steve R. Roffler)
    Huang WC, Burnouf PA, Su YC, Chen BM, Chuang KH, Lee CW, Wei PK, Cheng TL, Roffler SR (2016) Engineering Chimeric Receptors To Investigate the Size- and Rigidity-Dependent Interaction of PEGylated Nanoparticles with Cells. ACS Nano. 10(1):648-62 [PDF]

2015

  1. Chia-Sui Sun 孫嘉穗 (Advisor: Dr. Yijuang Chern and Dr. Joseph Jen-Tse Huang)
    Sun CS, Lee CC, Li YN, Yang SY, Lin CH, Chang YC, Liu PF, He RY, Wang CH, Chen W, Chern Y, Huang JJ. (2015) Conformational switch of polyglutamine-expanded huntingtin into benign aggregates leads to neuroprotective effect. Sci Rep. 5:14992. [PDF]
  2. Ai-Chung Mar 馬璦中 (Advisor: Dr. Te-Chang Lee)
    Mar AC, Chu CH, Lee HJ, Chien CW, Cheng JJ, Yang SH, Jiang JK, Lee TC. (2015) Interleukin-1 Receptor Type 2 Acts with c-Fos to Enhance the Expression of Interleukin-6 and Vascular Endothelial Growth Factor A in Colon Cancer Cells and Induce Angiogenesis. J Biol Chem. 290(36):22212-24. [PDF]
  3. Ying-Chi Chao 趙英淇 (Advisor: Dr. Ruey-Bing Yang)
    Chao YC, Chen CC, Lin YC, Breer H, Fleischer J, Yang RB. (2015) Receptor guanylyl cyclase-G is a novel thermosensory protein activated by cool temperatures. EMBO J. 34(3): 294-306. [PDF]
  4. Pei-Ying Lin 林佩瑩 (Advisor: Dr. Pan-Cher Yang and Dr. Konan Peck)
    Lin PY, Chang SN, Hsiao TH, Huang BT, Lin CH, Yang PC. (2015) Association Between Parkinson Disease and Risk of Cancer in Taiwan. JAMA Oncol. doi:10.1001/jamaoncol.2015.1752 [PDF]
  5. Hsin-Yi Tung 童馨儀 (Advisor: Dr. Steve R. Roffler)
    Tung HY, Su YC, Chen BM, Burnouf PA, Huang WC, Chuang KH, Yan YT, Cheng TL, Roffler SR. (2015) Selective Delivery of PEGylated Compounds to Tumor Cells by Anti-PEG Hybrid Antibodies. Mol Cancer Ther. 14(6): 1317–26. [PDF]
  6. Yogy Simanjuntak 史曼均 (Advisor: Dr. Yi-Ling Lin)
    Simanjuntak Y, Liang JJ, Lee YL, Lin YL. (2015) Repurposing of prochlorperazine for use against dengue virus infection. J Infect Dis. 211(3):394-404. [PDF]
  7. Wen-Chuan Shen 沈文荃 (Advisor: Dr. Pang-Hsien Tu and Dr. Yijuang Chern)
    Shen WC, Li HY, Chen GC, Chern Y, Tu PH. (2015) Mutations in the ubiquitin-binding domain of OPTN/optineurin interfere with autophagy-mediated degradation of misfolded proteins by a dominant-negative mechanism. Autophagy 11(4):685-700. [PDF]
  8. Irfan Naseem Bandey 潘爾納 (Advisor: Dr. Pang-Hsien Tu)
    Bandey I, Chiou SH, Huang AP, Tsai JC, Tu PH (2015) Progranulin promotes Temozolomide resistance of glioblastoma by orchestrating DNA repair and tumor stemness. Oncogene 34(14):1853-64. [PDF]

2014

  • Chia-Sui Sun 孫嘉穗 (Advisor: Dr. Yijuang Chern and Dr. Joseph Jen-Tse Huang)
    Sun CS, Wang CY Chen BP, He RY, Liu GC, Wang CH, Chen W, Chern Y, Huang JJ. (2014) The Influence of Pathological Mutations and Proline Substitutions in TDP-43 Glycine-Rich Peptides on Its Amyloid Properties and Cellular Toxicity. PLoS ONE 9(8): e103644. [PDF]
  • Wei-Ting Chen 陳暐婷 (Advisor: Dr. Irene Han-Juo Cheng)
    Chen WT, Hsieh YF, Huang YJ, Lin CC, Lin YT, Liu YC, Lien CC, Cheng IH. (2014) G206D Mutation of Presenilin-1 Reduces Pen2 Interaction, Increases Aβ42/Aβ40 Ratio and Elevates ER Ca2+ Accumulation. Mol Neurobiol. DOI:10.1007/s12035-014-8969-1. [PDF]
  • Kai-Ting Chen 陳凱婷 (Advisor: Dr. Hsei-Wei Wang)
    Chen KT, Pernelle K, Tsai YH, Wu YH, Hsieh JY, Liao KH, Guguen-Guillouzo C, Wang HW. (2014) Liver X receptor α (LXRα/NR1H3) regulates differentiation of hepatocyte-like cells via reciprocal regulation of HNF4α. J Hepatol. 61(6):1276-86. [PDF]
  • Cheng-Fen Tu 凃瀞芬 (Advisor: Dr. Ruey-Bing Ray Yang)
    Tu CF, Tsao KC, Lee SJ, Yang RB. (2014) SCUBE3 (Signal Peptide-CUB-EGF Domain-containing Protein 3) Modulates Fibroblast Growth Factor Signaling during Fast Muscle Development. J Biol Chem. 289(27):18928-42. [PDF]
  • Wei-Yun Lai 賴薇云 (Advisor: Dr. Pan-Cher Yang and Dr. Konan Peck)
    Lai WY, Chen CY, Yang SC, Wu JY, Chang CJ, Yang PC, Peck K. Overcoming EGFR T790M-based Tyrosine Kinase Inhibitor Resistance with an Allele-specific DNAzyme. Molecular Therapy Nucleic Acids (2014) 3, e150. [PDF]

2013

  • Yi-Chih Wu 吳宜之 (Advisor: Dr. Yijuang Chern)
    Wu YC, Lai HL, Chang WC, Lin JT, Liu YJ, Chern Y. (2013) A novel Gαs-binding protein, Gas-2 like 2, facilitates the signaling of the A2A adenosine receptor. Biochim Biophys Acta. (12):3145-54. [PDF]
  • Yu-Wang Chang 張裕旺 (Advisor: Dr. Chien-Chang Chen)
    Chang YW, Chang YT, Wang Q, Lin JJ, Chen YJ, Chen CC. (2013) Quantitative phosphoproteomic study of pressure-overloaded mouse heart reveals dynamin-related protein 1 as a modulator of cardiac hypertrophy. Mol Cell Proteomics. 12(11):3094-107. [PDF]
  • Shao-Chun Hsu 許紹君 (Advisor: Dr. Chien-Chang Chen)
    Hsu SC, Chang YT, Chen CC. (2013) Early growth response 1 is an early signal inducing Cav3.2 T-type calcium channels during cardiac hypertrophy. Cardiovasc Res. 100(2):222-30. [PDF]
  • Cheng-Pu Sun 孫承溥 (Advisor: Dr. Mi-Hua Tao)
    Sun CP, Wu TH, Chen CC, Wu PY, Shih YM, Tsuneyama K, Tao MH. (2013) Studies of efficacy and liver toxicity related to adeno-associated virus-mediated RNA interference. Hum Gene Ther. 24(8):739-50. [PDF]
  • Hsiao-Hui Tseng 曾曉慧 (Advisor: Dr. Danny Ling Wang)
    Tseng AH, Shieh SS, Wang DL. (2013) SIRT3 deacetylates FOXO3 to protect mitochondria against oxidative damage. Free Radic Biol Med. 63:222-34. [PDF]

2012

  • Wei-Chih Yang 楊偉志 (Advisor: Dr. Hsiu-Ming Shih)
    Yang WC and Shih HM. (2013) The deubiquitinating enzyme USP37 regulates the oncogenic fusion protein PLZF/RARA stability. Oncogene. 32(43):5167-75. [PDF]
  • Wen-Yu Pan 潘玟伃 (Advisor: Dr. Mi-Hua Tao)
    Pan WY, Lo CH, Chen CC, Wu PY, Roffler SR, Shyue SK, Tao MH. (2012) Cancer immunotherapy using a membrane-bound interleukin-12 with B7-1 transmembrane and cytoplasmic domains. Mol Ther. 20(5):927-37. [PDF]
  • Chun-Yu Wei 魏淳郁 (Advisor: Dr. Yuan-Tsong Chen and Dr. Shuen-Iu Hung)
    Wei CY, Chung WH, Huang HW, Chen YT, Hung SI. (2012) Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome. J Allergy Clin Immunol. 129(6):1562-9. [PDF]
  • Chia-Ching Lin 林家靖 (Advisor: Dr. Chih-Cheng Chen)
    Lin CC, Chen WN, Chen CJ, Lin YW, Zimmer A, Chen CC. (2012) An antinociceptive role for substance P in acid-induced chronic muscle pain. Proc Natl Acad Sci U S A. 109(2):E76-83. [PDF]
  • Kumar Sanjiv 薩克瑪 (Advisor: Dr. Lee, Te-Chang)
    Sanjiv K, Su TL, Suman S, Kakadiya R, Lai TC, Wang HY, Hsiao M, Lee TC. (2012) The novel DNA alkylating agent BO-1090 suppresses the growth of human oral cavity cancer in xenografted and orthotopic mouse models. Int J Cancer. 130(6):1440-50. [PDF]

2011

  • Wei-Lun Hwang 黃尉倫 (Advisor: Dr. Hsei-Wei Wang)
    Hwang WL, Yang MH, Tsai ML, Lan HY, Su SH, Chang SC, Teng HW, Yang SH, Lan YT, Chiou SH, Wang HW. (2011) SNAIL regulates interleukin-8 expression, stem cell-like activity, and tumorigenicity of human colorectal carcinoma cells. Gastroenterology. 141(1):279-91. [PDF]
  • Huei-Ying Li 李慧瑛 (Advisor: Dr. Pang-Hsien Tu)
    Li HY, Yeh PA, Chiu HC, Tang CY, Tu BP. (2011) Hyperphosphorylation as a defense mechanism to reduce TDP-43 aggregation. PLoS One. 6(8):e23075. [PDF]
  • Abd-Al-Ahad nagham George 艾妮荷 (Advisor: Dr. Yuan-Tsong Chen)
    Sabbagha NG, Kao HJ, Yang CF, Huang CC, Lin WD, Tsai FJ, Chen TH, Tarn WY, Wu JY, Chen YT. (2011) Alternative splicing in Acad8 resulting a mitochondrial defect and progressive hepatic steatosis in mice. Pediatr Res. 70(1):31-6. [PDF]

2008

  • Wen-Hung Chung 鐘文宏 (Advisor: Dr. Yuan-Tsong Chen)
    Chung WH, Hung SI, Yang JY, Su SC, Huang SP, Wei CY, Chin SW, Chiou CC, Chu SC, Ho HC, Yang CH, Lu CF, Wu JY, Liao YD, Chen YT. (2008) Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis. Nat Med. 14(12):1343-50. [PDF]