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ACADEMIA SINICA INSTITUTE OF BIOMEDICAL SCIENCES
背景圖
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::: research resources

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UniProbe

Database:

UniProbe

Principal Investigator:Dr. Peck, Konan

Introduction:
Gene-specific oligonucleotide probes are currently used in microarrays to avoid cross-hybridization of highly similar sequences.


SpecificP

Database:

SpecificP

Principal Investigator:Dr. Peck, Konan

Introduction:
Mammalian genomes are highly complex. To identify the unique sequences of each gene in a mammalian gene database containing tens of thousands of DNA sequences is a computation intensive task.


ViralProbe

Database:

ViralProbe

Principal Investigator:Dr. Peck, Konan

Introduction:
Most virus detection methods are geared towards the detection of specific single viruses or just a few known targets, and lack the capability to uncover the novel viruses that cause emerging viral infections.

 


 

Vir-Mir

Database:

Vir-Mir

Principal Investigator: Dr. Lin, Wen-Chang

Introduction: Virus microRNA prediction and targets

MicroRNAs have been found in various organisms and play essential roles in gene expression regulation of many critical cellular processes.


uman intronic miRNA

Database:

Human intronic miRNA

Principal Investigator: Dr. Lin, Wen-Chang

Introduction: Intronic miRNA and targets

Identification of microRNAs (miRNAs) is essential to studying their physiological functions.


TDL-InDel

Database:

TDL-InDel

Principal Investigator: Dr. Lin, Wen-Chang

Introduction: Single amino acid InDels by splicing

We have investigated putative single amino-acid InDel variants with human ESTs.


TDL-CGI

Database:

TDL-CGI

Principal Investigator: Dr. Lin, Wen-Chang

Introduction: Human gene discovery by ESTs

Modern biomedical research greatly benefits from large-scale genome-sequencing projects ranging from studies of viruses, bacteria, and yeast to multicellular organisms, like Caenorhabditis elegans.

 


 

IGDB.NSCLC

Database:

IGDB.NSCLC

Principal Investigator:Dr. Jou, Yuh-Shan

Introduction:Integrated genomic database of non-small cell lung cancer

IGDB.NSCLC provides user friendly interfaces and searching functions to display multiple layers of evidence especially emphasizing on concordant alterations of CNAs with co-localized altered gene expression …


IGRhCellID

Database:

IGRhCellID

Principal Investigator:Dr. Jou, Yuh-Shan

Introduction:Integrated genomic resources of human cell lines for identification

Cell line identification is emerging as an essential method for every cell line user in research community to avoid using misidentified cell lines for experiments and publications …


OncoDB.HCC

Database:

OncoDB.HCC

Principal Investigator:Dr. Jou, Yuh-Shan

Introduction:Oncogenomic Database of Hepatocellular Carcinoma

The OncoDB.HCC (http://oncodb.hcc.ibms.sinica.edu.tw) is based on physical maps of rodent and human genomes containing quantitative …


TPMD

Database:

TPMD (Link1) (Link2)

Principal Investigator:Dr. Jou, Yuh-Shan

Introduction:Taiwan Polymorphic Marker Database

Taiwan Polymorphic Marker Database (TPMD) is a marker database designed to provide experimental details and useful marker information

 


 

VisualSNP

Database:

VisualSNP

Principal Investigator:Dr. Yao, Wen-Hsuang

Introduction: Functional SNP Prioritization Tool


GenoWatch

Database:

GenoWatch

Principal Investigator:Dr. Yao, Wen-Hsuang

Introduction: Vigorous Gene Mining


QualiSeq

Database:

QualiSeq

Principal Investigator:Dr. Yao, Wen-Hsuang

Introduction: Quality Genomic Sequence Retrieval


PrimerZ

Database:

PrimerZ

Principal Investigator:Dr. Yao, Wen-Hsuang

Introduction: Streamlining Primer Design for Genes and SNPs

PrimerZ is a web application dedicated primarily to primer design for genes and human SNPs.

SeqTool

Database:

SeqTool

Principal Investigator:Dr. Yao, Wen-Hsuang

Introduction: SNP flanking sequence download for Sequenom


GenePipe

Database:

GenePipe

Principal Investigator:Dr. Yao, Wen-Hsuang

Introduction: Bioinformatics Pipeline for IBMS Genetic Research


FANS

Database:

FANS

Principal Investigator:Dr. Yao, Wen-Hsuang

Introduction: Functional Analysis for Novel SNPs and Mutations


iSample

Database:

iSample

Principal Investigator:Dr. Yao, Wen-Hsuang

Introduction: Laboratory Resource Management


iQuestion

Database:

iQuestion

Principal Investigator:Dr. Yao, Wen-Hsuang

Introduction: iQuestion is a web application for Questionnaire or Case Report Form (CRF) Design and Management.

Some key features of iQuestion include Questionnaire or CRF design, data capture, data management and dataset export in common statistical analysis formats.

 


 

VHMPS

Database:

VHMPS

Principal Investigator:Dr. Hwang, Ming-Jing

Introduction:Viewer and editor for Helical Membrane Protein Topologies.

Lacking structures resolved at atomic resolution, the great majority of membrane proteins have typically been depicted in a schematic two-dimensional (2D) topology consisting of putative transmembrane domains predicted…


VACPS

Database:

VACPS

Principal Investigator:Dr. Hwang, Ming-Jing

Introduction: Viewing Amino-acid Conservation on Protein Structures.


HaploScape

Database:

HaploScape

Principal Investigator:Dr. Hwang, Ming-Jing

Introduction: 人類haplotype-tag SNPs資料庫


UniMarker

Database:

UniMarker

Principal Investigator:Dr. Hwang, Ming-Jing

Introduction:

  1. As more and more genomic DNAs are sequenced to characterize human genetic variations, the demand for a very fast and accurate method to genomically position these DNA sequences is high.
  2. Synteny mapping, or detecting regions that are orthologous between two genomes, is a key step in studies of comparative genomics.

HMDEG

Database:

HMDEG

Principal Investigator:Dr. Hwang, Ming-Jing

Introduction: A database for human and mouse differentially expressed genes.

Screening for differentially expressed genes on the genomic scale and comparative analysis of the expression profiles of orthologous genes between species to study gene function and regulation are becoming increasingly feasible.


OPAAS

Database:

OPAAS

Principal Investigator:Dr. Hwang, Ming-Jing

Introduction: Optimal, Permuted and Other Alternative Alignments of Protein Structures.

  1. Protein structure comparison (PSC) has been used widely in studies of structural and functional genomics.
  2. Comparison of two protein structures often results in not only a global alignment but also a number of distinct local alignments…
  3. The large number of experimentally determined protein 3D structures is a rich resource for studying protein function and evolution…

Foldzilla

Database:

Foldzilla

Principal Investigator:Dr. Hwang, Ming-Jing

Introduction: 蛋白質結構核資料庫


PROPEAT

Database:

PROPEAT

Principal Investigator:Dr. Hwang, Ming-Jing

Introduction:A Database for Protein Structural Repeats.