Dr. Huang, Yi-Shuian

Olfactory-Experience- and Developmental-Stage-Dependent Control of CPEB4 Regulates c-Fos mRNA Translation for Granule Cell Survival

Cell Reports, Nov 21, 2017

Summary: Mammalian olfactory bulbs (OBs) require continuous replenishment of interneurons (mainly granule cells [GCs]) to support local cir ......

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Dr. Huang, Yi-Shuian

CPEB2 Activates GRASP1 mRNA Translation and Promotes AMPA Receptor Surface Expression, Long-Term Potentiation, and Memory

Cell Reports, Nov 14, 2017

Summary: Activity-dependent synthesis of plasticity-related proteins is necessary to sustain long-lasting synaptic modifications and consol ......

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Dr. Wu, Jer-Yuarn

A genome-wide association study links small-vessel ischemic stroke to autophagy

Scientific Reports, Nov 09, 2017

Genome-wide association studies (GWAS) can serve as strong evidence in correlating biological pathways with human diseases. Although ischemi ......

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Dr. Huang, Yi-Shuian

Decoding hidden messages in neurons: insights from epitranscriptome-controlled and specialized ribosome-controlled translation

Current Opinion in Neurobiology, Nov 07, 2017

Activity-regulated protein synthesis, especially in the restricted synaptic domains, is critical to maintaining connections and communicatio ......

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Dr. Shih, Chiaho

Heparin at physiological concentration can enhance PEG-free in vitro infection with human hepatitis B virus

Scientific Reports, Oct 31, 2017

Hepatitis B virus (HBV) is a blood-borne pathogen responsible for chronic hepatitis, cirrhosis, and liver cancer. The mechanism of HBV entry ......

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Dr. Hu, Che-Ming (Jack)

Targeting and Enrichment of Viral Pathogen by Cell Membrane Cloaked Magnetic Nanoparticles for Enhanced Detection

ACS Applied Materials & Interfaces, Oct 31, 2017

Attachment to cellular surfaces is a major attribute among infectious pathogens for initiating disease pathogenesis. In viral infections, vi ......

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Dr. Hwang, Ming-Jing

A proteome view of structural, functional, and taxonomic characteristics of major protein domain clusters

Scientific Reports, Oct 27, 2017

Proteome-scale bioinformatics research is increasingly conducted as the number of completely sequenced genomes increases, but analysis of pr ......

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Dr. Chen, Chien-Chang

Cardioprotection induced in a mouse model of neuropathic pain via anterior nucleus of paraventricular thalamus

Nature Communications, Oct 10, 2017

Myocardial infarction is the leading cause of death worldwide. Restoration of blood flow rescues myocardium but also causes ischemia-reperfu ......

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Dr. Yang, Ruey-Bing (Ray)

FUT8 promotes breast cancer cell invasiveness by remodeling TGF-β receptor core fucosylation

Breast Cancer Research, Oct 05, 2017

Background Core fucosylation (addition of fucose in α-1,6-linkage to core N-acetylglucosamine of N-glycans) catalyzed by fuco ......

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Dr. Yang, Ruey-Bing (Ray)

Guanylyl cyclase‐G is an alarm pheromone receptor in mice

EMBO Journal, Sep 28, 2017

Many animals respond to threats by releasing alarm pheromones (APs) that warn conspecifics. In mice, detection of the AP 2‐sec‐butyl‐4,5‐dih ......

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