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Dr. Steve Roffler

IBMS

Academia Sinica

sroff@ibms.sinica.edu.tw

(Tel) 886-2-2652-3079

 

 

Mr. David Cheng

Academia Sinica

PEG@gate.sinica.edu.tw

(Tel) 886-2-2787-2503

(Fax) 886-2-2651-8049

 

 

 

 

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Anti-PEG Antibody News

 

April 2012  Review of methods to measure PEGylated compounds in biological samples.

 

June 2010  New anti-PEG antibodies allow sensitive detection of PEGylated compounds

AGP4 and 3.3-biotin allow sensitive detection of PEGylated proteins, nanoparticles and lipodsomes in complex biological samples.

 

May 2010   Universal anti-PEG receptors for imaging of PEGylated compounds

Expression of anti-PEG antibodies on cells can increase liposome and imaging uptake in cancer cells.

 

April 2010   Anti-PEG receptors enhances uptake of PEGylated compounds

Expression of anti-PEG antibodies on cells can increase liposome and imaging uptake in cancer cells.

 

March 2010   Novel PEG assay

We have developed a novel cell based assay to measure PEG in solution. You can read the publication here

 

2-04-09 Antibody comparison

We compared several of our antibodies with antibodies from other sources for sandwich ELISA. The combination of AGP4 for capture and 3.3-biotin for detection worked well for all tested PEGylated compounds and out-performed antibodies from other vendors.

Detailed results

 

 

12-25-08 New price schedule on selected antibodies

The price of our established antibodies has been reduced due to the availability of our new AGP4 and 3.3 antibodies.

 

 

12-15-08 New anti-PEG antibodies are now available

We have several new anti-PEG antibodies available.

AGP4 is a new IgM that displays similar or slightly higher binding activity to PEG than AGP3. A biotinylated version AGP4-biotin is also available for detection. AGP4 works especially well as a capture antibody for sandwich ELISAs. Lower concentrations of AGP4 (0.25 mg/well) capture PEGylated compounds more effectively than 1 mg/well AGP3!

 

3.3-biotin is a new high affinity IgG1 monoclonal anti-PEG antibody. This antibody displays higher affinity for PEG than E11 and is an effective detection antibody.