戴榮湘 博士Activation of Multifarious Transcription of an Adhesion Protein Ap65-1 Gene by a Novel Myb2 Protein in the Protozoan Parasite Trichomonas Vaginalis.
J. Biol. Chem, Mar 02, 2007
Multifarious transcription of the adhesion protein ap65-1 gene in the human pathogen, Trichomonas vaginalis, is critically regulated by t ......
張久瑗 博士Osteopontin Promotes Integrin Activation through Outside-In and Inside-Out Mechanisms: OPN-CD44V Interaction Enhances Survival in Gastrointestinal Cancer Cells.
Cancer Research, Mar 01, 2007
Osteopontin (OPN) and splice variants of CD44 (CD44V) have independently been identified as markers for tumor progression. In this study, ......
趙麗洋 博士Systemic Expression of Heme Oxygenase-1 Ameliorates Type 1 Diabetes in Nod.
Diabetes., Feb 15, 2007
Heme oxygenase-1 (HO-1) is an enzyme with potent immunoregulatory capacity. To evaluate the effect of HO-1 on autoimmune diabetes, female ......
蕭百忍 博士Partial duplication at AZFc on the Y chromosome is a risk factor for impaired spermatogenesis in Han Chinese in Taiwan.
Human Mutation., Feb 06, 2007
The Azoospermia Factor c (AZFc) region on the Y chromosome long arm is one of the least stable regions in the human genome. It consists a ......
譚婉玉 博士Cell stress modulates the function of splicing regulatory protein RBM4 in translation control.
Proc Natl Acad Sci USA., Feb 06, 2007
RNA-binding motif protein 4 (RBM4) plays a regulatory role in alternative splicing of precursor mRNA. We show here that cell stress such ......
沈志陽 博士Genetic Variation in the Premature Aging Gene WRN: A Case-Control Study on Breast Cancer usceptibility.
Cancer Epidemiology Biomarkers & Prevention., Feb 01, 2007
The high risk of developing cancer seen in human genetic diseases that resemble accelerated aging provides support for a tumorigenic cont ......
陳儀莊 博士Systematic uncovering of multiple pathways underlying the pathology of Huntington's disease by an acid-cleavable isotope-coded affinity tag approach.
Molecular & Cellular Proteomics., Jan 31, 2007
Huntington disease (HD) is an autosomal dominant neurodegenerative disease that results from a CAG (glutamine) trinucleotide expansion in ......
陳儀莊 博士Dysregulation of C/EBPa by mutant Huntingtin causes the urea cycle deficiency in Huntington's disease.
Hum Mol Genet., Jan 09, 2007
Huntington's disease (HD) is an autosomal dominant neurodegenerative disease caused by a CAG trinucleotide expansion in the Huntingti ......
沈志陽 博士Breast Cancer Risk Associated with Genotypic Polymorphism of the Mitotic Checkpoint Genes: a ultigenic Study on Cancer Susceptibility.
Carcinogenesis., Jan 08, 2007
Aneuploidy occurs early during tumorigenesis and may contribute to tumor formation. Tumor cells become aneuploid as a result of aberrant ......
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