Novel antitumor indolizino[6,7-b]indoles with multiple modes of action: DNA cross-linking and topoisomerase I and II inhibition.
J Med Chem., Jan 29, 2013
A series of bis(hydroxymethyl)indolizino[6,7-b]indoles and their bis(alkylcarbamates) were synthesized for antitumor studies. These agents w ......
MCPIP1 ribonuclease exhibits broad-spectrum antiviral effects through viral RNA binding and degradation.
Nucleic Acids Res., Jan 25, 2013
Monocyte chemoattractant protein 1-induced protein 1 (MCPIP1), belonging to the MCPIP family with highly conserved CCCH-type zinc finger and ......
RBM4 Promotes Pancreas Cell Differentiation and Insulin Expression.
Mol Cell Biol., Jan 13, 2013
The RNA-binding protein RNA-binding motif protein 4 (RBM4) modulates alternative splicing of muscle-specific mRNA isoforms during muscle cel ......
Hyaluronan Enhances Bone Marrow Cell Therapy for Myocardial Repair After Infarction.
Mol Ther., Jan 08, 2013
Hyaluronan (HA) has been shown to play an important role during early heart development and promote angiogenesis under various physiological ......
The RNA-binding protein Y14 inhibits mRNA decapping and modulates processing body formation.
Mol Biol Cell., Jan 01, 2013
The exon-junction complex (EJC) deposited on a newly spliced mRNA plays an important role in subsequent mRNA metabolic events. Here we show ......