劉扶東 博士Galectin-7 Regulates Keratinocyte Proliferation and Differentiation through JNK-miR-203-p63 Signaling.
Journal of Investigative Dermatology, Sep 22, 2015
Galectin-7, a member of the β-galactoside-binding protein family, is primarily expressed in stratified epithelial cells, including kera ......
謝清河 博士Nanoparticle distribution during systemic inflammation is size-dependent and organ-specific.
Nanoscale., Sep 11, 2015
This study comprehensively investigates the changing biodistribution of fluorescent-labelled polystyrene latex bead nanoparticles in a mouse ......
洪士杰 博士Allo-transplantation of Mesenchymal Stem Cells Attenuates Hepatic Injury through IL1Ra Dependent Macrophage Switch in a Mouse Model of Liver Disease.
J Hepatol., Aug 11, 2015
Autologous transplantation of mesenchymal stem cells (MSCs) reduces concanavalin A (Con A)-induced hepatic injury in mice. However, the mech ......
陳儀莊 博士Elucidating the role of the A2A adenosine receptor in neurodegeneration using neurons derived from Huntington's disease iPSCs.
Hum. Mol. Genet., Aug 11, 2015
Huntington's disease (HD) is an autosomal dominant degenerative disease caused by a CAG trinucleotide expansion in the Huntingtin (htt) ......
范盛娟 博士Genetic determinants of antithyroid drug-induced agranulocytosis by human leukocyte antigen genotyping and genome-wide association study.
Nat Commun., Jul 07, 2015
Graves' disease is the leading cause of hyperthyroidism affecting 1.0-1.6% of the population. Antithyroid drugs are the treatment corner ......
林榮信 博士Recovery of the poisoned topoisomerase II for DNA religation: coordinated motion of the cleavage core revealed with the microsecond atomistic simulation.
Nucleic Acids Res., Jul 06, 2015
Type II topoisomerases resolve topological problems of DNA double helices by passing one duplex through the reversible double-stranded break ......
陳垣崇 博士Cyclic Alopecia and Abnormal Epidermal Cornification in Zdhhc13 Deficient Mice Reveals the Importance of Palmitoylation in Hair and Skin Differentiation.
J Invest Dermatol., Jun 29, 2015
Many biochemical pathways involved in hair and skin development have not been investigated. Here, we reported on the lesions and investigate ......
林天南 博士PPAR-γ Ameliorates Neuronal Apoptosis and Ischemic Brain Injury via Suppressing NF-κB-Driven p22phox Transcription.
Mol Neurobiol., Jun 25, 2015
Peroxisome proliferator-activated receptor-gamma (PPAR-γ), a stress-induced transcription factor, protects neurons against ischemic st ......
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