李小媛 博士

MeCP2 SUMOylation rescues Mecp2-mutant-induced behavioural deficits in a mouse model of Rett syndrome.

Nature Communications, Feb 04, 2016

Dr. Eminy H.Y. Lee, Distinguished Research Fellow at the Institute of Biomedical Sciences, Academia Sinica recently discovered that modifica ......

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李小媛 博士

SUMO modification of Akt regulates global SUMOylation and substrate SUMOylation specificity through Akt phosphorylation of Ubc9 and SUMO1

Oncogene, Feb 04, 2016

SUMOylation is an important post-translational modification, and Akt SUMOylation was found to regulate cell proliferation, tumorigenesis and ......

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黃明經 博士

Proteins with highly evolvable domain architectures are non-essential but highly retained.

Mol Biol Evol., Jan 14, 2016

The functions of proteins are usually determined by domains, and the sequential order in which domains are connected to make up a protein ch ......

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羅傅倫 博士

Engineering Chimeric Receptors to Investigate the Size and Rigidity-Dependent Interaction of PEGylated Nanoparticles with Cells.

ACS Nano., Jan 07, 2016

Attachment of ligands to the surface of nanoparticles (NPs) is an attractive approach to target specific cells and increase intracellular de ......

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