謝清河 博士Human iPSC banking: barriers and opportunities
Journal of Biomedical Science, Oct 28, 2019
The introduction of induced pluripotent stem cells (iPSCs) has opened up the potential for personalized cell therapies and ushered in new op ......
嚴仲陽 博士Palmitoyl acyltransferase activity of ZDHHC13 regulates skin barrier development partly by controlling PADi3 and TGM1 protein stability
Journal of Investigative Dermatology, Oct 25, 2019
Deficiency of the palmitoyl-acyl transferase ZDHHC13 compromises skin barrier permeability and renders mice susceptible to environmental bac ......
林小喬 博士Free and Bound Therapeutic Lithium in Brain Signaling
Accounts of Chemical Research, Sep 26, 2019
Lithium, a first-line therapy for bipolar disorder, is effective in preventing suicide and new depressive/manic episodes. Yet, how this begu ......
林文昌 博士Overlapping protein-coding genes in human genome and their coincidental expression in tissues
Scientific Reports, Sep 16, 2019
The completion of human genome sequences and the advancement of next-generation sequencing technologies have engendered a clear understandin ......
張雅貞 博士TLR9-dependent interferon production prevents group 2 innate lymphoid cell-driven airway hyperreactivity
Journal of Allergy and Clinical Immunology, Sep 01, 2019
Background: Group 2 innate lymphoid cells (ILC2s) are important mediators of allergic asthma. Bacterial components such as unmethylated CpG ......
陳儀莊 博士Functional roles of ST8SIA3-mediated sialylation of striatal dopamine D2 and adenosine A2A receptors
Translational Psychiatry, Aug 27, 2019
Sialic acids are typically added to the end of glycoconjugates by sialyltransferases. Among the six ST8 α-N-acetyl-neuraminide α ......
謝清河 博士Hypoxia-induced H19/YB-1 cascade modulates cardiac remodeling after infarction
Theranostics, Aug 21, 2019
Rationale: Long non-coding RNA (lncRNAs) has been identified as a pivotal novel regulators in cardiac development as well as cardiac pathoge ......
李永凌 博士Assessing Causality Between Childhood Adiposity and Early Puberty: A Bidirectional Mendelian Randomization and Longitudinal Study
Metabolism, Aug 15, 2019
Aims
Obesity and early puberty have been reported to be mutually causative. We investigated the causal relationship between adiposity a ......
潘文涵 博士Is Hyperuricemia, an Early-Onset Metabolic Disorder, Causally Associated with Cardiovascular Disease Events in Han Chinese?
Journal of Clinical Medicine, Aug 12, 2019
Background: Serum uric acid (SUA) has gradually been recognized as a potential risk factor for cardiovascular disease (CVD). However, whethe ......
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