潘文涵 博士

Adequate protein intake in older adults in the context of frailty: cross-sectional results of the Nutrition and Health Survey in Taiwan 2014–2017

The American Journal of Clinical Nutrition, Aug 02, 2021

    Background Emerging evidence suggests that a dietary protein intake higher than the current recommended dietary all ......

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周玉山 博士

PSPC1 is a new contextual determinant of aberrant subcellular translocation of oncogenes in tumor progression

Journal of Biomedical Science, Aug 02, 2021

    Dysregulation of nucleocytoplasmic shuttling is commonly observed in cancers and emerging as a cancer hallmark for the d ......

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陳儀莊 博士

Contribution of Energy Dysfunction to Impaired Protein Translation in Neurodegenerative Diseases

Frontiers in Cellular Neuroscience, Jul 28, 2021

    Impaired energy homeostasis and aberrant translational control have independently been implicated in the pathogenesis of ......

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李永凌 博士

Effects of obesity on pulmonary function considering the transition from obstructive to restrictive pattern from childhood to young adulthood

Obesity Reviews, Jul 28, 2021

    Adults with obesity exhibit a restrictive pattern, whereas children with obesity exhibit an obstructive pattern. However ......

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劉扶東 博士

Galectin-3 promotes noncanonical inflammasome activation through intracellular binding to lipopolysaccharide glycans

PNAS, Jul 27, 2021

    Cytosolic lipopolysaccharides (LPSs) bind directly to caspase-4/5/11 through their lipid A moiety, inducing inflammatory ......

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楊泮池 博士

Potential therapeutics using tumor-secreted lactate in nonsmall cell lung cancer

Drug Discovery Today, Jul 26, 2021

    Targeted-therapy failure in treating nonsmall cell lung cancer (NSCLC) frequently occurs because of the emergence of dru ......

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沈志陽 博士

Rare variants discovery by extensive whole-genome sequencing of the Han Chinese population in Taiwan: Applications to cardiovascular medicine.

J Adv Res., Jul 01, 2021

The human genome contains an enormous amount of informa-tion about human evolution, development, and medicine. To dis-cover the underlying g ......

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陳儀莊 博士

Equilibrative nucleoside transporter 1 inhibition rescues energy dysfunction and pathology in a model of tauopathy

Acta Neuropathologica Communications, Jun 25, 2021

Tau pathology is instrumental in the gradual loss of neuronal functions and cognitive decline in tauopathies, including Alzheimer’s di ......

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蔡松智 博士

Epitranscriptomic addition of m6A regulates HIV-1 RNA stability and alternative splicing

Genes & Development, Jun 17, 2021

    Previous work has demonstrated that the epitranscriptomic addition of m6A to viral transcripts can promote the replicati ......

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唐堂 博士

Human Microcephaly Protein RTTN Is Required for Proper Mitotic Progression and Correct Spindle Position

Cells, Jun 09, 2021

    Autosomal recessive primary microcephaly (MCPH) is a complex neurodevelopmental disorder characterized by a small brain ......

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