The gut microbiota regulates acute foreign body reaction and tissue repair after biomaterial implantation

Biomaterials Sep 19, 2022

We hypothesized that the host microbiome may influence foreign body responses following biomaterial implantation. To tes ......

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楊鎧鍵博士

The novel role of ER protein TXNDC5 in the pathogenesis of organ fibrosis: mechanistic insights and therapeutic implications

Journal of Biomedical Science Sep 02, 2022

Fibrosis-related disorders account for an enormous burden of disease-associated morbidity and mortality worldw ......

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楊瑞彬博士

Signal peptide-CUB-EGF-like repeat-containing protein 1-promoted FLT3 signaling is critical for the initiation and maintenance of MLL-rearranged acute leukemia

Haematologica Aug 25, 2022

A hallmark of mixed lineage leukemia gene-rearranged (MLL-r) acute myeloid leukemia (AML) that offers an oppor ......

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潘文涵博士

Common and Ethnic-Specific Genetic Determinants of Hemoglobin Concentration between Taiwanese Han Chinese and European Whites: Findings from Comparative Two-Stage Genome-Wide Association Studies

Journal of Nutritional Biochemistry Aug 11, 2022

Human iron nutrition is a result of interplays between genetic and environmental factors. However, there has b ......

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潘文涵博士

Healthy Taiwanese Eating Approach (TEA) toward Total Wellbeing and Healthy Longevity

Nutrients Jul 05, 2022

A healthy dietary pattern review for Asian countries is scarce, which is crucial for guiding healthy eating. W ......

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陳建璋博士

Cav3.2 T-type calcium channel regulates mouse platelet activation and arterial thrombosis

Journal of thrombosis and haemostasis Jul 01, 2022

Background Cav3.2 is a T-type calcium channel that causes low-threshold exocytosis. T-type calcium channe ......

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陳建璋博士

Multiomic analyses reveal enriched glycolytic processes in β-myosin heavy chain-expressed cardiomyocytes in early cardiac hypertrophy

Journal of Molecular and Cellular Cardiology Plus Jun 27, 2022

Background Cardiac pressure overload induces cardiac hypertrophy and eventually leads to heart ......

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胡瑜峰博士

Fibroblasts Drive Metabolic Reprogramming in Pacemaker Cardiomyocytes

Circulation Research Jun 24, 2022

Methods: Tbx18 (T-box transcription factor 18)-induced PCs and fibroblasts were used for cocultures and e ......

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楊瑞彬博士

Plasma Galectin-9 Is a Useful Biomarker for Predicting Renal Function in Patients Undergoing Native Kidney Biopsy

Archives of pathology & laboratory medicine Jun 10, 2022

Objective.—: To investigate the association between plasma galectin-9 levels, proteinuria, tubuloin ......

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謝清河博士

Utility of iPSC-Derived Cells for Disease Modeling, Drug Development, and Cell Therapy

Cells Jun 06, 2022

The advent of induced pluripotent stem cells (iPSCs) has advanced our understanding of the molecular mechanism ......

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