林文昌 博士

Dominant transcript expression profiles of human protein-coding genes interrogated with GTEx dataset

Scientific Reports Apr 28, 2022

      The discovery and quantification of mRNA transcripts using short-read next-generation sequencing (NGS) data is ......

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周玉山 博士

Prognostic comparative genes predict targets for sorafenib combination therapies in hepatocellular carcinoma

Comput Struct Biotechnol J Apr 20, 2022

      With the increasing incidence and mortality of human hepatocellular carcinoma (HCC) worldwide, revealing innov ......

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牟昀 博士

Development of a TNF-α-mediated Trojan Horse for Bacteria-based Cancer Therapy

Molecular Therapy Apr 19, 2022

      TNF-α is up-regulated in a chronic inflammatory environment, including tumors, and has been recognized a ......

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唐堂 博士

A novel HIF1α-STIL-FOXM1 axis regulates tumor metastasis

Journal of Biomedical Science Apr 01, 2022

    Background Metastasis is the major cause of morbidity and mortality in cancer that involves in multiple steps includi ......

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牟昀 博士

Fragment-Directed Random Mutagenesis by the Reverse Kunkel Method

ACS Synthetic Biology Mar 24, 2022

      Two fundamentally different approaches are routinely used for protein engineering: user-defined mutagenesis an ......

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唐堂 博士

Modeling Human Primary Microcephaly With hiPSC-Derived Brain Organoids Carrying CPAP-E1235V Disease-Associated Mutant Protein

Frontiers in Cell and Developmental Biology Mar 02, 2022

      The centrosome is composed of a pair of centrioles and serves as the major microtubule-organizing center (MTOC ......

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楊泮池 博士

Metasurface-Based Abrupt Autofocusing Beam for Biomedical Applications

Small Methods Feb 24, 2022

      Manipulation and precise delivery of optical energies in the regions of interest within specimens require diff ......

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楊泮池 博士

A siRNA targets and inhibits a broad range of SARS-CoV-2 infections including Delta variant

EMBO Molecular Medicine Feb 21, 2022

      The emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants has altered the traject ......

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沈志陽 博士

Genome-wide association study identifies genetic risk loci for adiposity in a Taiwanese population

PLOS Genetics Jan 20, 2022

  Overweight and obese are risk factors for various diseases. In Taiwan, the combined prevalence of overweight and obesity has incre ......

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沈志陽 博士

A common variant in 11q23.3 associated with hyperlipidemia is mediated by the binding and regulation of GATA4

npj Genomic Medicine Jan 19, 2022

      Large-scale genome-wide associations comprising multiple studies have identified hundreds of genetic loci comm ......

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