林文昌 博士

Vir-Mir db: prediction of viral microRNA candidate hairpins.

Nucleic Acids Research. Aug 15, 2007

MicroRNAs have been found in various organisms and play essential roles in gene expression regulation of many critical cellular processes ......

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楊泮池 博士

Targeting Neuropilin 1 as an Antitumor Strategy in Lung Cancer.

Clinical Cancer Research. Aug 15, 2007

Neuropilin 1 (NRP1) is a mediator of lung branching and angiogenesis in embryonic development and angiogenesis in cancer. The role of NRP ......

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謝小燕 博士

The candidate tumor suppressor BTG3 is a transcriptional target of p53 that inhibits E2F1

The EMBO Journal Aug 09, 2007

Proper regulation of cell cycle progression is pivotal for maintaining genome stability. In a search for DNA damage-inducible, CHK1-modul ......

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林文昌 博士

Wobble splicing reveals the role of the BPS-to-NAGNAG region in 3' tandem splice site selection.

Mol. Cell. Biol. Jun 11, 2007

Alternative splicing involving the 3' tandem splice site NAGNAG may play a role in structure-function diversity of proteins. However, ......

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趙麗洋 博士

Systemic Expression of Heme Oxygenase-1 Ameliorates Type 1 Diabetes in Nod.

Diabetes. Feb 15, 2007

Heme oxygenase-1 (HO-1) is an enzyme with potent immunoregulatory capacity. To evaluate the effect of HO-1 on autoimmune diabetes, female ......

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沈志陽 博士

Genetic Variation in the Premature Aging Gene WRN: A Case-Control Study on Breast Cancer usceptibility.

Cancer Epidemiology Biomarkers & Prevention. Feb 01, 2007

The high risk of developing cancer seen in human genetic diseases that resemble accelerated aging provides support for a tumorigenic cont ......

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沈志陽 博士

Breast Cancer Risk Associated with Genotypic Polymorphism of the Mitotic Checkpoint Genes: a ultigenic Study on Cancer Susceptibility.

Carcinogenesis. Jan 08, 2007

Aneuploidy occurs early during tumorigenesis and may contribute to tumor formation. Tumor cells become aneuploid as a result of aberrant ......

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楊泮池 博士

A Five-Gene Signature and Clinical Outcome in Non–Small-Cell Lung Cancer.

N Engl J Med. Jan 04, 2007

Current staging methods are inadequate for predicting the outcome of treatment of non–small-cell lung cancer (NSCLC). We developed ......

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