沈志陽博士

Inhibitory Effects of Ursolic Acid on the Stemness and Progression of Human Breast Cancer Cells by Modulating Argonaute-2

International Journal of Molecular Sciences Dec 26, 2022

The stemness and metastasis of cancer cells are crucial features in determining cancer progression. Argonaute- ......

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周玉山博士

Somatic A-to-I RNA-edited RHOA isoform 2 specific-R176G mutation promotes tumor progression in lung adenocarcinoma

Molecular Carcinogenesis Dec 01, 2022

Adenosine-to-inosine (A-to-I) RNA editing is the most common posttranscriptional editing to create somatic mut ......

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陳世淯博士

Spatial multi-omics analyses of the tumor immune microenvironment

Journal of Biomedical Science Nov 14, 2022

In the past decade, single-cell technologies have revealed the heterogeneity of the tumor-immune microenvironment at the genomic, transcript ......

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李玲慧博士

Enrichment of Prevotella intermedia in human colorectal cancer and its additive effects with Fusobacterium nucleatum on the malignant transformation of colorectal adenomas

Journal of Biomedical Science Oct 27, 2022

Methods: Microbiota composition was determined through 16S rRNA V3-V4 amplicon sequencing of autologous a ......

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李家偉博士

Deglycosylation of SLAMF7 in breast cancers enhances phagocytosis

American Journal of Cancer Research Oct 15, 2022

N-linked glycosylation of proteins is one of the post-translational modifications (PTMs) that shield tumor ant ......

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林文昌博士

TEx-MST: tissue expression profiles of MANE select transcripts

Database(Oxford) Sep 28, 2022

Recently, a new reference transcript dataset [Matched Annotation from the NCBI and EMBL-EBI (MANE) select] was ......

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楊泮池博士

Stage Shift Improves Lung Cancer Survival: Real-World Evidence

Journal of Thoracic Oncology Sep 18, 2022

Introduction Lung cancer is the global leading cause of cancer death. Taiwan initiated several health polic ......

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謝小燕博士

JAK2-CHK2 signaling safeguards the integrity of the mitotic spindle assembly checkpoint and genome stability

Cell Death & Disease Jul 18, 2022

Checkpoint kinase 2 (CHK2) plays an important role in safeguarding the mitotic progression, specifically the s ......

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施修明博士

Reciprocal regulation of Daxx and PIK3CA promotes colorectal cancer cell growth

Cellular and Molecular Life Sciences Jun 19, 2022

Upregulation of death-domain-associated protein (Daxx) is strongly associated with diverse cancer types. Among ......

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張久瑗博士

Patient-Derived Organoid Serves as a Platform for Personalized Chemotherapy in Advanced Colorectal Cancer Patients

Frontiers in Oncology Jun 01, 2022

Background: Addition of oxaliplatin to adjuvant 5-FU has significantly improved the disease-free survival ......

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