李家偉 博士

Epithelial-mesenchymal transition induced by SARS-CoV-2 required transcriptional upregulation of Snail

American Journal of Cancer Research May 15, 2021

  Abstract The engagement of human angiotensin-converting enzyme 2 (hACE2) and SARS-CoV-2 spike protein facilitate virus spread ......

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楊泮池 博士

Vorinostat combined with brigatinib overcomes acquired resistance in EGFR-C797S-mutated lung cancer

Cancer Letters Mar 26, 2021

    Abstract The development of a new generation of tyrosine kinase inhibitors (TKIs) has improved the treatment respon ......

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鈴木淳 博士

Caspase cleavage releases a nuclear protein fragment that stimulates phospholipid scrambling at the plasma membrane

Molecular Cell Mar 15, 2021

Summary Phospholipid scrambling in dying cells promotes phosphatidylserine exposure, a critical process for efferocytosis. We ......

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楊泮池 博士

PINK1-mediated inhibition of EGFR dimerization and activation impedes EGFR-driven lung tumorigenesis

Cancer Research Feb 09, 2021

  EGFR is established as a driver of lung cancer, yet the regulatory machinery underlying its oncogenic activity is not fully unders ......

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趙麗洋 博士

Siglec-E retards atherosclerosis by inhibiting CD36-mediated foam cell formation

Journal of Biomedical Science Jan 05, 2021

Abstract Background The accumulation of lipid-laden macrophages, foam cells, within sub-endothelial intima is a key feature of early a ......

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