Dr. Liu, Fu-Tong

Ablation of a galectin preferentially expressed in adipocytes increases lipolysis, reduces adiposity, and improves insulin sensitivity in mice

PNAS, Sep 12, 2011

The breakdown of triglycerides, or lipolysis, is a tightly controlled process that regulates fat mobilization in accord with an animal's ......


Dr. Chen, Chinpan

Structure of the Trichomonas vaginalis Myb3 DNA-binding domain bound to a promoter sequence reveals a unique C-terminal β-hairpin conformation

Nucl. Acids Res., Sep 08, 2011

Trichomonas vaginalis Myb3 transcription factor (tvMyb3) recognizes the MRE-1 promoter sequence and regulates ap65-1 gene, which encodes a h ......


Dr. Lee, Eminy H.Y.

Laminin-β1 Impairs Spatial Learning through Inhibition of ERK/MAPK and SGK1 Signaling.

Neuropsychopharmacology, Aug 17, 2011

Laminin is a major structural element of the basal lamina consisting of an α-chain, a β-chain, and a γ-chain arranged in a ......


Dr. Yang, Pan-Chyr

The ability of LCRMP-1 to promote cancer invasion by enhancing filopodia formation is antagonized by CRMP-1.

J Clin Invest., Aug 01, 2011

Metastasis is a predominant cause of death in patients with cancer. It is a complex multistep process that needs to be better understood if ......


Dr. Huang, Tai-huang

Molecular basis of the recognition of the ap65-1 gene transcription promoter elements by a Myb protein from the protozoan parasite Trichomonas vaginalis

Nucl. Acids Res., Jul 19, 2011

Iron-inducible transcription of the ap65-1 gene in Trichomonas vaginalis involves at least three Myb-like transcriptional factors (tvMyb1, t ......


Dr. Pan, Wen-Harn

A Genome-Wide Association Study Reveals a Quantitative Trait Locus of Adiponectin on CDH13 That Predicts Cardiometabolic Outcomes.

Diabetes, Jul 19, 2011

The plasma adiponectin level, a potential upstream and internal facet of metabolic and cardiovascular diseases, has a reasonably high herita ......


Dr. Chern, Yijuang

Nuclear translocation of AMPK-α1 potentiates striatal neurodegeneration in Huntington』s disease.

JCB, Jul 18, 2011

Adenosine monophosphate–activated protein kinase (AMPK) is a major energy sensor that maintains cellular energy homeostasis. Huntingto ......


Dr. Wu, Jer-Yuarn

Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.

Nature Genetics, May 15, 2011

We conducted a meta-analysis of genome-wide association studies of systolic (SBP) and diastolic (DBP) blood pressure in 19,608 subjects of e ......


Dr. Shih, Hsiu-Ming

Structural and Functional Roles of Daxx SIM Phosphorylation in SUMO Paralog-Selective Binding and Apoptosis Modulation.

Molecular Cell, May 08, 2011

Small ubiquitin-like modifier (SUMO) conjugation and interaction are increasingly associated with various cellular processes. However, littl ......


Dr. Tarn, Woan-Yuh

RBM4 down-regulates PTB and antagonizes its activity in muscle cell–specific alternative splicing.

JCB., May 02, 2011

Alternative splicing contributes largely to cell differentiation and functional specification. We previously reported that the RNA-binding p ......


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