Dr. Yang, Pan-Chyr

SCUBE3 is an endogenous TGF-β receptor ligand and regulates the epithelial-mesenchymal transition in lung cancer.

Oncogene., Mar 28, 2011

Signal peptide-CUB-EGF-like domain-containing protein 3 (SCUBE3) is a secreted glycoprotein that is overexpressed in lung cancer tumor tissu ......


Dr. Shen, Chen-Yang

Carbamazepine-Induced Toxic Effects and HLA-B*1502 Screening in Taiwan.

N Engl J Med., Mar 24, 2011

Carbamazepine, an anticonvulsant and a mood-stabilizing drug, is the main cause of the Stevens–Johnson syndrome (SJS) and its related ......


Dr. Pan, Wen-Harn

Common Carotid End-Diastolic Velocity and Intima-Media Thickness Jointly Predict Ischemic Stroke in Taiwan.

Stroke, Mar 17, 2011

In Asian populations, few studies investigated the association between stroke and common carotid artery intima-media thickness (IMT). Our pr ......


Dr. Chern, Yijuang

Dysregulated brain creatine kinase is associated with hearing impairment in mouse models of Huntington disease.

J Clin Invest., Mar 14, 2011

Huntington disease (HD) is a dominant neurodegenerative disorder that usually becomes established in middle age. The clinical features inclu ......


Dr. Yang, Pan-Chyr

Enterovirus-Induced miR-141 Contributes to Shutoff of Host Protein Translation by Targeting the Translation Initiation Factor eIF4E.

Cell Host & Microbe, Jan 20, 2011

Viruses rely on the host translation machinery to complete their life cycles. Picornaviruses use an internal ribosome entry site to initiate ......


Dr. Chen, Steve S.-L.

Autophagy: A novel guardian of HCV against innate immune response

Autophagy, Jan 01, 2011

Autophagy is an evolutionarily conserved process that catabolizes intracellular components and maintains cellular homeostasis. Autophagy inv ......


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