Dr. Hsieh , Patrick Ching-Ho Immune cell shuttle for precise delivery of nanotherapeutics for heart disease and cancer
Science Advances Apr 23, 2021The delivery of therapeutics through the circulatory system is one of the least arduous and less invasive inte ......
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Dr. Pan , Wen-Harn Adequate protein intake in older adults in the context of frailty: cross-sectional results of the Nutrition and Health Survey in Taiwan 2014–2017
The American Journal of Clinical Nutrition Apr 13, 2021Background Emerging evidence suggests that a dietary protein intake higher than the current recommended dietary all ......
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Dr. Chang , Yi-Cheng Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices
Nature Communications Apr 12, 2021Autosomal genetic analyses of blood lipids have yielded key insights for coronary heart disease (CHD). However, X chromosome genetic v ......
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Dr. Yang , Ruey-Bing (Ray)Zebrafish scube1 and scube2 cooperate in promoting Vegfa signaling during embryonic vascularization
Cardiovascular Research Mar 31, 2021Aims The secreted and membrane-anchored signal peptide-CUB-EGF domain-containing proteins (SCUBE) gene family compo ......
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Dr. Hu , Che-Ming (Jack) Robust induction of TRMs by combinatorial nanoshells confers cross-strain sterilizing immunity against lethal influenza viruses
Methods & Clinical Development Mar 23, 2021Antigen-specific lung-resident memory T cells (TRMs) constitute the first line of defense that mediates rapid prote ......
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Dr. Hu , Che-Ming (Jack) Nanotechnology advances in pathogen- and host-targeted antiviral delivery: multipronged therapeutic intervention for pandemic control
Drug Delivery and Translational Research Mar 21, 2021The COVID-19 pandemic's high mortality rate and severe socioeconomic impact serve as a reminder of the urgent need f ......
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Dr. Chang , Yi-Cheng A Novel ALDH2 Activator AD-9308 Improves Diastolic and Systolic Myocardial Functions in Streptozotocin-Induced Diabetic Mice
Antioxidants Mar 13, 2021Diabetes mellitus has reached epidemic proportion worldwide. One of the diabetic complications is cardiomyopathy, characterized by early lef ......
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Dr. Chang , Yi-Cheng Th17 helper T cells: a new actor on the stage of type 2 diabetes and ageing?
Diabetes Investig Mar 08, 2021In conclusion, the elegant work by Bharath et al. provides a new link between IL-17 and aging, and highlighted the immunosupp ......
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Dr. Chang , Yi-Cheng Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program
Nature Feb 10, 2021The Trans-Omics for Precision Medicine (TOPMed) programme seeks to elucidate the genetic architecture and biology of heart, lung, bloo ......
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Dr. Yang , Kai-Chien Endoplasmic reticulum protein TXNDC5 promotes renal fibrosis by enforcing TGFβ signaling in kidney fibroblasts
Journal of Clinical Investigation Jan 19, 2021Abstract Renal fibrosis, a common pathological manifestation of virtually all types of chronic kidney diseases (CKD), often results in di ......
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