Dr. Lee , Te-Chang

Promoter hypermethylation of LGALS4 correlates with poor prognosis in patients with urothelial carcinoma

Oncotarget Apr 04, 2017

Galectine-4 (gal-4), encoded by the LGALS4 gene, was recently shown to exhibit a tumor suppressive effect in colorectal carcinoma and pancre ......

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Dr. Shen , Chen-Yang

B-Myb Induces APOBEC3B Expression Leading to Somatic Mutation in Multiple Cancers

Scientific Reports Mar 09, 2017

The key signature of cancer genomes is the accumulation of DNA mutations, the most abundant of which is the cytosine-to-thymine (C-to-T) tra ......

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Dr. Lee , Te-Chang

P-glycoprotein attenuates DNA repair activity in multidrug-resistant cells by acting through the Cbp-Csk-Src cascade

Oncotarget Feb 03, 2017

Recent studies have demonstrated that P-glycoprotein (P-gp) expression impairs DNA interstrand cross-linking agent-induced DNA repair effici ......

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