Dr. Yang , Ruey-Bing (Ray)

Receptor guanylyl cyclase‐G is a novel thermosensory protein activated by cool temperatures.

EMBO J. Dec 01, 2014

Transmembrane guanylyl cyclases (GCs), with activity regulated by peptide ligands and/or calcium‐binding proteins, are essential for various ......

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Dr. Hsieh , Patrick Ching-Ho

Circulating Cells Contribute to Cardiomyocyte Regeneration After Injury.

Circ Res. Nov 14, 2014

Rationale: The contribution of bone marrow-borne hematopoietic cells to the ischemic myocardium has been documented. However, a pivotal stud ......

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Dr. Chau , Lee-Young

Signal peptide peptidase-mediated nuclear localization of heme oxygenase-1 promotes cancer cell proliferation and invasion independent of its enzymatic activity.

Oncogene. Jun 16, 2014

Heme oxygenase-1 (HO-1) is a heme-degrading enzyme anchored in the endoplasmic reticulum by a carboxyl-terminal transmembrane segment (TMS). ......

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Dr. Yang , Ruey-Bing (Ray)

SCUBE3 (Signal Peptide-CUB-EGF Domain-containing Protein 3) Modulates Fibroblast Growth Factor Signaling during Fast Muscle Development.

JBC. May 21, 2014

SCUBE3 (signal peptide CUB-EGF-like domain-containing protein 3) belongs to a newly identified secreted and cell membrane-associated SCUBE f ......

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Dr. Yang , Ruey-Bing (Ray)

Inhibition of the Plasma SCUBE1, a Novel Platelet Adhesive Protein, Protects Mice Against Thrombosis.

Arterioscler Thromb Vasc Biol. May 15, 2014

Signal peptide-CUB-EGF domain-containing protein 1 (SCUBE1), a secreted and surface-exposed glycoprotein on activated platelets, promotes pl ......

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Dr. Chen , Chien-Chang

Cav3.2 T-type calcium channel is required for the NFAT-dependent Sox9 expression in tracheal cartilage.

PNAS Apr 28, 2014

The tracheal cartilage rings are important for protecting and maintaining the airway. However, the chondrogenesis of tracheal cartilage is n ......

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Dr. Hsieh , Patrick Ching-Ho

Prostaglandin E2 promotes post-infarction cardiomyocyte replenishment by endogenous stem cells.

EMBO Mol Med. Jan 21, 2014

Although self-renewal ability of adult mammalian heart has been reported, few pharmacological treatments are known to promote cardiomyocyte ......

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Dr. Hsieh , Patrick Ching-Ho

Clearance Kinetics of Biomaterials Affects Stem Cell Retention and Therapeutic Efficacy.

Biomacromolecules. Jan 06, 2014

The use of biomaterial carriers to improve the therapeutic efficacy of stem cells is known to augment cell delivery, retention, and viabilit ......

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