Dr. Pan , Wen-Harn The Mediterranean diet reduces the genetic risk of chromosome 9p21 for myocardial infarction in an Asian population community cohort
Scientific Reports Dec 05, 2019The interaction of genetic susceptibility and dietary habits in cardiovascular disease (CVD) remains undetermined. The purpose of this study ......
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Dr. Pan , Wen-Harn Individualized home-based exercise and nutrition interventions improve frailty in older adults: a randomized controlled trial
International Journal of Behavioral Nutrition and Physical Activity Dec 02, 2019Background Frail older adults are predisposed to multiple comorbidities and adverse events. Recent interventional studies have shown that ......
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Dr. Pan , Wen-Harn The causal role of elevated uric acid and waist circumference on the risk of metabolic syndrome components
International Journal of Obesity Nov 21, 2019Background/objectives Hyperuricemia has been found to cluster with multiple components of metabolic syndrome (MetS). It is unclear whethe ......
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Dr. Hsieh , Patrick Ching-Ho Human iPSC banking: barriers and opportunities
Journal of Biomedical Science Oct 28, 2019The introduction of induced pluripotent stem cells (iPSCs) has opened up the potential for personalized cell therapies and ushered in new op ......
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Dr. Cheng , Ching-Feng Adipocyte browning and resistance to obesity in mice is induced by expression of ATF3
Communications Biology Oct 24, 2019Billions of people have obesity-related metabolic syndromes such as diabetes and hyperlipidemia. Promoting the browning of white adipose tis ......
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Dr. Hsieh , Patrick Ching-Ho Hypoxia-induced H19/YB-1 cascade modulates cardiac remodeling after infarction
Theranostics Aug 21, 2019Rationale: Long non-coding RNA (lncRNAs) has been identified as a pivotal novel regulators in cardiac development as well as cardiac pathoge ......
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Dr. Hwang , Ming-Jing Risk stratification for lung adenocarcinoma on EGFR and TP53 mutation status, chemotherapy, and PD‐L1 immunotherapy
Cancer Medicine Aug 13, 2019The overall survival rates for lung cancer remain unsatisfactorily low, even for patients with biomarkers for which target therapies or immu ......
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Dr. Pan , Wen-Harn Is Hyperuricemia, an Early-Onset Metabolic Disorder, Causally Associated with Cardiovascular Disease Events in Han Chinese?
Journal of Clinical Medicine Aug 12, 2019Background: Serum uric acid (SUA) has gradually been recognized as a potential risk factor for cardiovascular disease (CVD). However, whethe ......
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Dr. Hsieh , Patrick Ching-Ho MicroRNA let-7-TGFBR3 signalling regulates cardiomyocyte apoptosis after infarction
EBioMedicine Aug 07, 2019Background Myocardial infarction (MI) is a life-threatening disease, often leading to heart failure. Defining therapeutic targets at an ......
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Dr. Cheng , Ching-Feng Targeting Protein Tyrosine Phosphatase PTP-PEST for Therapeutic Intervention in Acute Myocardial Infarction
Cardiovascular Research Jun 22, 2019Aims The myocardial ischemia/reperfusion (I/R) injury is almost inevitable since reperfusion is the only established treatment for acut ......
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