Dr. Hsieh , Patrick Ching-Ho

The gut microbiota regulates acute foreign body reaction and tissue repair after biomaterial implantation

Biomaterials Sep 19, 2022

    We hypothesized that the host microbiome may influence foreign body responses following biomaterial implantation. To tes ......

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Dr. Yang , Kai-Chien

The novel role of ER protein TXNDC5 in the pathogenesis of organ fibrosis: mechanistic insights and therapeutic implications

Journal of Biomedical Science Sep 02, 2022

      Fibrosis-related disorders account for an enormous burden of disease-associated morbidity and mortality worldw ......

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Dr. Yang , Ruey-Bing (Ray)

Signal peptide-CUB-EGF-like repeat-containing protein 1-promoted FLT3 signaling is critical for the initiation and maintenance of MLL-rearranged acute leukemia

Haematologica Aug 25, 2022

      A hallmark of mixed lineage leukemia gene-rearranged (MLL-r) acute myeloid leukemia (AML) that offers an oppor ......

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Dr. Pan , Wen-Harn

Common and Ethnic-Specific Genetic Determinants of Hemoglobin Concentration between Taiwanese Han Chinese and European Whites: Findings from Comparative Two-Stage Genome-Wide Association Studies

Journal of Nutritional Biochemistry Aug 11, 2022

      Human iron nutrition is a result of interplays between genetic and environmental factors. However, there has b ......

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Dr. Pan , Wen-Harn

Healthy Taiwanese Eating Approach (TEA) toward Total Wellbeing and Healthy Longevity

Nutrients Jul 05, 2022

      A healthy dietary pattern review for Asian countries is scarce, which is crucial for guiding healthy eating. W ......

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Dr. Chen , Chien-Chang

Cav3.2 T-type calcium channel regulates mouse platelet activation and arterial thrombosis

Journal of thrombosis and haemostasis Jul 01, 2022

      Background Cav3.2 is a T-type calcium channel that causes low-threshold exocytosis. T-type calcium channe ......

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Dr. Chen , Chien-Chang

Multiomic analyses reveal enriched glycolytic processes in β-myosin heavy chain-expressed cardiomyocytes in early cardiac hypertrophy

Journal of Molecular and Cellular Cardiology Plus Jun 27, 2022

      Background Cardiac pressure overload induces cardiac hypertrophy and eventually leads to heart ......

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Dr. Hu , Yu-Feng

Fibroblasts Drive Metabolic Reprogramming in Pacemaker Cardiomyocytes

Circulation Research Jun 24, 2022

      Methods: Tbx18 (T-box transcription factor 18)-induced PCs and fibroblasts were used for cocultures and e ......

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Dr. Yang , Ruey-Bing (Ray)

Plasma Galectin-9 Is a Useful Biomarker for Predicting Renal Function in Patients Undergoing Native Kidney Biopsy

Archives of pathology & laboratory medicine Jun 10, 2022

      Objective.—: To investigate the association between plasma galectin-9 levels, proteinuria, tubuloin ......

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Dr. Hsieh , Patrick Ching-Ho

Utility of iPSC-Derived Cells for Disease Modeling, Drug Development, and Cell Therapy

Cells Jun 06, 2022

      The advent of induced pluripotent stem cells (iPSCs) has advanced our understanding of the molecular mechanism ......

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