Dr. Wu , Cheng-Wen Coexpression of Oct4 and Nanog Enhances Malignancy in Lung Adenocarcinoma by Inducing Cancer Stem Cell–Like Properties and Epithelial–Mesenchymal Transdifferentiation.
Cancer Res. Dec 15, 2010Epithelial–mesenchymal transition (EMT), a critical process of cancer invasion and metastasis, is associated with stemness property of ......
detail
Dr. Lin , Wen-chang dbDNV: a resource of duplicated gene nucleotide variants in human genome.
Nucleic Acids Res Nov 21, 2010Gene duplications are scattered widely throughout the human genome. A single-base difference located in nearly identical duplicated segments ......
detail
Dr. Jou , Yuh-Shan IGRhCellID: integrated genomic resources of human cell lines for identification.
Nucleic Acids Research Nov 04, 2010Cell line identification is emerging as an essential method for every cell line user in research community to avoid using misidentified cell ......
detail
Dr. Wu , Cheng-Wen EGFR Promotes Lung Tumorigenesis by Activating miR-7 through a Ras/ERK/Myc Pathway That Targets the Ets2 Transcriptional Repressor ERF.
Cancer Res. Nov 01, 2010MicroRNAs (miRNA) mediate distinct gene regulatory pathways triggered by epidermal growth factor receptor (EGFR) activation, which occurs co ......
detail
Dr. Jou , Yuh-Shan Overlapping high-resolution copy number alterations in cancer genomes identified putative cancer genes in hepatocellular carcinoma.
Hepatology Aug 31, 2010Recurrent cancer genome aberrations are indicators of residing crucial cancer genes. Although recent advances in genomic technologies have l ......
detail
Dr. Shen , Chen-Yang Diverse Associations between ESR1 Polymorphism and Breast Cancer Development and Progression.
Clinical Cancer Research Jun 22, 2010To test the hypothesis that polymorphisms of ESR1, the gene encoding estrogen receptor α (ERα), are associated with susceptibili ......
detail
Dr. Shih , Hsiu-Ming Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability.
J Cell Biol. Jun 21, 2010Mitotic spindles play essential roles in chromosome congression and segregation during mitosis. Aurora A regulates spindle assembly in part ......
detail
Dr. Roffler , Steve R. Cutting Edge: Mechanical Forces Acting on T Cells Immobilized via the TCR Complex Can Trigger TCR Signaling.
J Immunology Apr 30, 2010Engagement of the TCR by antigenic peptides presented by the MHC activates specific T cells to control infections. Recent theoretical consid ......
detail
Dr. Shieh , Sheau-Yann p53-Mediated transactivation of LIMK2b links actin dynamics to cell cycle checkpoint control.
Oncogene Mar 01, 2010The p53 tumor suppressor protein is widely known for its role as a sequence-specific transcription factor that regulates the expression of s ......
detail| Record 1 to 9, total of 9 records |
