Hypoxia is a major driving force of cancer invasion and metastasis. Here we show that death domain-associated protein (Daxx) acts to negativ ......
detailClinical virotherapy has been successfully approved for use in cancer treatment by the U.S. Food and Drug Administration; however, a number ......
detailTumor microenvironment (TME) plays an active role in promoting tumor progression. To further understand the communication between TME and tu ......
detailPolyethylene glycol (PEG) is a biocompatible polymer that is often attached to therapeutic molecules to improve bioavailability and therapeu ......
detailTargeting tumour-initiating cells (TICs) would lead to new therapies to cure cancer. We previously demonstrated that TICs have the capacity ......
detailDevelopment of colorectal cancer (CRC) involves sequential transformation of normal mucosal tissues into benign adenomas and then adenomas i ......
detailCPAP is required for centriole elongation during S/G2 phase, but the role of CPAP in mitosis is incompletely understood. Here, we show that ......
detailThe epithelial-to-mesenchymal (EMT) transition is a prerequisite for conferring metastatic potential during tumor progression. microRNA-30a ......
detailAttachment of ligands to the surface of nanoparticles (NPs) is an attractive approach to target specific cells and increase intracellular de ......
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