Dr. Chen , Shih-Yu

Spatial multi-omics analyses of the tumor immune microenvironment

Journal of Biomedical Science Nov 14, 2022

In the past decade, single-cell technologies have revealed the heterogeneity of the tumor-immune microenvironment at the genomic, transcript ......

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Dr. Li , Ling-Hui

Enrichment of Prevotella intermedia in human colorectal cancer and its additive effects with Fusobacterium nucleatum on the malignant transformation of colorectal adenomas

Journal of Biomedical Science Oct 27, 2022

      Methods: Microbiota composition was determined through 16S rRNA V3-V4 amplicon sequencing of autologous a ......

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Dr. Li , Chia-Wei

Deglycosylation of SLAMF7 in breast cancers enhances phagocytosis

American Journal of Cancer Research Oct 15, 2022

      N-linked glycosylation of proteins is one of the post-translational modifications (PTMs) that shield tumor ant ......

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Dr. Lin , Wen-chang

TEx-MST: tissue expression profiles of MANE select transcripts

Database(Oxford) Sep 28, 2022

      Recently, a new reference transcript dataset [Matched Annotation from the NCBI and EMBL-EBI (MANE) select] was ......

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Dr. Yang , Pan-Chyr

Stage Shift Improves Lung Cancer Survival: Real-World Evidence

Journal of Thoracic Oncology Sep 18, 2022

      Introduction Lung cancer is the global leading cause of cancer death. Taiwan initiated several health polic ......

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Dr. Shieh , Sheau-Yann

JAK2-CHK2 signaling safeguards the integrity of the mitotic spindle assembly checkpoint and genome stability

Cell Death & Disease Jul 18, 2022

      Checkpoint kinase 2 (CHK2) plays an important role in safeguarding the mitotic progression, specifically the s ......

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Dr. Shih , Hsiu-Ming

Reciprocal regulation of Daxx and PIK3CA promotes colorectal cancer cell growth

Cellular and Molecular Life Sciences Jun 19, 2022

      Upregulation of death-domain-associated protein (Daxx) is strongly associated with diverse cancer types. Among ......

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Dr. Chen , Joanne Jeou-Yuan

Patient-Derived Organoid Serves as a Platform for Personalized Chemotherapy in Advanced Colorectal Cancer Patients

Frontiers in Oncology Jun 01, 2022

      Background: Addition of oxaliplatin to adjuvant 5-FU has significantly improved the disease-free survival ......

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Dr. Lin , Wen-chang

Dominant transcript expression profiles of human protein-coding genes interrogated with GTEx dataset

Scientific Reports Apr 28, 2022

      The discovery and quantification of mRNA transcripts using short-read next-generation sequencing (NGS) data is ......

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Dr. Jou , Yuh-Shan

Prognostic comparative genes predict targets for sorafenib combination therapies in hepatocellular carcinoma

Comput Struct Biotechnol J Apr 20, 2022

      With the increasing incidence and mortality of human hepatocellular carcinoma (HCC) worldwide, revealing innov ......

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