Dr. Chen , Shih-Yu
Spatial multi-omics analyses of the tumor immune microenvironment
Journal of Biomedical Science Nov 14, 2022
In the past decade, single-cell technologies have revealed the heterogeneity of the tumor-immune microenvironment at the genomic, transcript ......
Dr. Li , Ling-Hui
Enrichment of Prevotella intermedia in human colorectal cancer and its additive effects with Fusobacterium nucleatum on the malignant transformation of colorectal adenomas
Journal of Biomedical Science Oct 27, 2022
Methods: Microbiota composition was determined through 16S rRNA V3-V4 amplicon sequencing of autologous a ......
Dr. Li , Chia-Wei
Deglycosylation of SLAMF7 in breast cancers enhances phagocytosis
American Journal of Cancer Research Oct 15, 2022
N-linked glycosylation of proteins is one of the post-translational modifications (PTMs) that shield tumor ant ......
Dr. Lin , Wen-chang
TEx-MST: tissue expression profiles of MANE select transcripts
Sep 28, 2022
Recently, a new reference transcript dataset [Matched Annotation from the NCBI and EMBL-EBI (MANE) select] was ......
Dr. Yang , Pan-Chyr
Stage Shift Improves Lung Cancer Survival: Real-World Evidence
Journal of Thoracic Oncology Sep 18, 2022
Lung cancer is the global leading cause of cancer death. Taiwan initiated several health polic ......
Dr. Shieh , Sheau-Yann
JAK2-CHK2 signaling safeguards the integrity of the mitotic spindle assembly checkpoint and genome stability
Cell Death & Disease Jul 18, 2022
Checkpoint kinase 2 (CHK2) plays an important role in safeguarding the mitotic progression, specifically the s ......
Dr. Shih , Hsiu-Ming
Reciprocal regulation of Daxx and PIK3CA promotes colorectal cancer cell growth
Cellular and Molecular Life Sciences Jun 19, 2022
Upregulation of death-domain-associated protein (Daxx) is strongly associated with diverse cancer types. Among ......
Dr. Chen , Joanne Jeou-Yuan
Patient-Derived Organoid Serves as a Platform for Personalized Chemotherapy in Advanced Colorectal Cancer Patients
Frontiers in Oncology Jun 01, 2022
Background: Addition of oxaliplatin to adjuvant 5-FU has significantly improved the disease-free survival ......
Dr. Lin , Wen-chang
Dominant transcript expression profiles of human protein-coding genes interrogated with GTEx dataset
Scientific Reports Apr 28, 2022
The discovery and quantification of mRNA transcripts using short-read next-generation sequencing (NGS) data is ......
Dr. Jou , Yuh-Shan
Prognostic comparative genes predict targets for sorafenib combination therapies in hepatocellular carcinoma
Comput Struct Biotechnol J Apr 20, 2022
With the increasing incidence and mortality of human hepatocellular carcinoma (HCC) worldwide, revealing innov ......