Student's Publication
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Mei-Han Kao 高媺涵 (Advisor: Dr. Teng-Nan Lin)
Activating Transcription Factor 3 Diminishes Ischemic Cerebral Infarct and Behavioral Deficit by Downregulating Carboxyl-Terminal Modulator Protein. Kao MH, Huang CY, Cheung WM, Yan YT, Chen JJ, Ho YS, Hsu CY, Lin TN. Int J Mol Sci. 2023 Jan 24;24(3):2306. doi: 10.3390/ijms24032306. PMID: 36768628 -
Vivia Khosasih 許慧慧 (Advisor: Dr. Jer-Yuarn Wu)
A Functional Polymorphism Downstream of Vitamin A Regulator Gene CYP26B1 Is Associated with Hand Osteoarthritis. Khosasih V, Liu KM, Huang CM, Liou LB, Hsieh MS, Lee CH, Tsai CY, Kuo SY, Hwa SY, Yu CL, Chang CH, Lin CJ, Hsieh SC, Cheng CY, Chen WM, Chen LK, Chuang HP, Chen YT, Tsai PC, Lu LS, H'ng WS, Zhang Y, Chen HC, Chen CH, Lee MTM, Wu JY. Int J Mol Sci. 2023 Feb 3;24(3):3021. doi: 10.3390/ijms24033021. PMID: 36769350 -
Chih-Hung Chung 鍾志宏 (Advisor: Dr. Muh-Hwa Yang)
Ferroptosis Signature Shapes the Immune Profiles to Enhance the Response to Immune Checkpoint Inhibitors in Head and Neck Cancer. Chung CH, Lin CY, Chen CY, Hsueh CW, Chang YW, Wang CC, Chu PY, Tai SK, Yang MH. Adv Sci (Weinh). 2023 May;10(15):e2204514. doi: 10.1002/advs.202204514. Epub 2023 Apr 7. PMID: 37026630 -
Hsiao-Han Tsai 蔡曉涵 (Advisor: Dr. Che-Ming J Hu)
Lymph Node Follicle-Targeting STING Agonist Nanoshells Enable Single-Shot M2e Vaccination for Broad and Durable Influenza Protection. Tsai HH, Huang PH, Lin LC, Yao BY, Liao WT, Pai CH, Liu YH, Chen HW, Hu CJ. Adv Sci (Weinh). 2023 Jun;10(17):e2206521. doi: 10.1002/advs.202206521. Epub 2023 Apr 24. PMID: 37092580 -
Chia-Hui Luo 駱佳慧 (Advisor: Dr. Ya-Jen Chang)
Butyrate inhibits Staphylococcus aureus-aggravated dermal IL-33 expression and skin inflammation through histone deacetylase inhibition. Luo CH, Lai AC, Chang YJ. Front Immunol. 2023 May 16;14:1114699. doi: 10.3389/fimmu.2023.1114699. eCollection 2023. PMID: 37261337 -
Chia-Yi Kao 高嘉宜 (Advisor: Dr. Kurt Yun Mou)
Improvement of Gene Delivery by Minimal Bacteriophage Particles. Kao CY, Pan YC, Hsiao YH, Lim SK, Cheng TW, Huang SW, Wu SM, Sun CP, Tao MH, Mou KY. ACS Nano. 2023 Aug 8;17(15):14532-14544. doi: 10.1021/acsnano.3c01295. Epub 2023 Jul 19. PMID: 37466994 -
Ha Thu Tran 陳秋荷 (Advisor: Dr. Chi-Ying F Huang)
Repurposing thioridazine for inducing immunogenic cell death in colorectal cancer via eIF2α/ATF4/CHOP and secretory autophagy pathways. Tran TH, Kao M, Liu HS, Hong YR, Su Y, Huang CF. Cell Commun Signal. 2023 Jul 24;21(1):184. doi: 10.1186/s12964-023-01190-5. PMID: 37488534 -
Jan Vincent Baloloy Beltran 簡文森 (Advisor: Dr. Tai-Ming Ko)
Single-Cell Meta-Analysis of Neutrophil Activation in Kawasaki Disease and Multisystem Inflammatory Syndrome in Children Reveals Potential Shared Immunological Drivers. Beltran JVB, Lin FP, Chang CL, Ko TM. Circulation. 2023 Oct 31. doi: 10.1161/CIRCULATIONAHA.123.064734. Online ahead of print. PMID: 37905415
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Ching-Chun Yang 楊清淳 (Advisor: Dr. Chiaho Shih)
CRM1-spike-mediated nuclear export of hepatitis B virus encapsidated viral RNA. Yang CC, Chang CH, Chen HL, Chou MC, Yang CJ, Jhou RS, Huang EY, Li HC, Suen CS, Hwang MJ, Shih C. Cell Rep. 2022 Mar 8;38(10):110472. doi: 10.1016/j.celrep.2022.110472. PMID: 35263598 -
Vanessa Joy Anico Timoteo 丁莫凡 (Advisor: Dr. Wen-Harn Pan)
Positive or U-Shaped Association of Elevated Hemoglobin Concentration Levels with Metabolic Syndrome and Metabolic Components: Findings from Taiwan Biobank and UK Biobank. Timoteo VJ, Chiang KM, Pan WH. Nutrients. 2022 Sep 27;14(19):4007. doi: 10.3390/nu14194007. PMID: 36235661 -
Hem Kumar Tamang 沈翰 (Advisor: Dr. Chien-Chang Chen)
Cav 3.2 T-type calcium channel regulates mouse platelet activation and arterial thrombosis. Tamang HK, Yang RB, Song ZH, Hsu SC, Peng CC, Tung YC, Tzeng BH, Chen CC. J Thromb Haemost. 2022 Aug;20(8):1887-1899. doi: 10.1111/jth.15745. Epub 2022 May 27. PMID: 35490411 -
Chiao Yin Lim 林喬寅 (Advisor: Dr. Ao-Lin Hsu)
SAMS-1 coordinates HLH-30/TFEB and PHA-4/FOXA activities through histone methylation to mediate dietary restriction-induced autophagy and longevity. Lim CY, Lin HT, Kumsta C, Lu TC, Wang FY, Kang YH, Hansen M, Ching TT, Hsu AL. Autophagy. 2022 May 3:1-17. doi: 10.1080/15548627.2022.2068267. Online ahead of print. PMID: 35503435 -
Wen-Hao Tsai 蔡文豪 (Advisor: Dr. Shi-Bing Yang)
Allosteric coupling between transmembrane segment 4 and the selectivity filter of TALK1 potassium channels regulates their gating by extracellular pH. Tsai WH, Grauffel C, Huang MY, Postić S, Rupnik MS, Lim C, Yang SB. J Biol Chem. 2022 Jun;298(6):101998. doi: 10.1016/j.jbc.2022.101998. Epub 2022 Apr 29. PMID: 35500647 -
Ting-Yun Yen 顏廷耘 (Advisor: Dr. Cheng-Chang Lien )
Inhibitory projections connecting the dentate gyri in the two hemispheres support spatial and contextual memory. Yen TY, Huang X, MacLaren DAA, Schlesiger MI, Monyer H, Lien CC. Cell Rep. 2022 May 17;39(7):110831. doi: 10.1016/j.celrep.2022.110831. PMID: 35584671 -
Md Al Nayem Chowdhury 周納言 (Advisor: Dr. Sheau-Yann Shieh)
JAK2-CHK2 signaling safeguards the integrity of the mitotic spindle assembly checkpoint and genome stability. Chowdhury MAN, Wang SW, Suen CS, Hwang MJ, Hsueh YA, Shieh SY. Cell Death Dis. 2022 Jul 18;13(7):619. doi: 10.1038/s41419-022-05077-0. PMID: 35851582 -
Yun-yun Wu 吳畇芸 (Advisor: Dr. Tzu-Hao Cheng)
Chemical interference with DSIF complex formation lowers synthesis of mutant huntingtin gene products and curtails mutant phenotypes. Deng N, Wu YY, Feng Y, Hsieh WC, Song JS, Lin YS, Tseng YH, Liao WJ, Chu YF, Liu YC, Chang EC, Liu CR, Sheu SY, Su MT, Kuo HC, Cohen SN, Cheng TH. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2204779119. doi: 10.1073/pnas.2204779119. Epub 2022 Aug 1. PMID: 35914128 -
Tania Devina 林丹妮 (Advisor: Dr. Irene Han-Juo Cheng)
Endoplasmic reticulum stress induces Alzheimer disease-like phenotypes in the neuron derived from the induced pluripotent stem cell with D678H mutation on amyloid precursor protein. Devina T, Wong YH, Hsiao CW, Li YJ, Lien CC, Cheng IH. J Neurochem. 2022 Aug 9. doi: 10.1111/jnc.15687. Online ahead of print. PMID: 35943292 -
Vanessa Joy Anico Timoteo 丁莫凡 (Advisor: Dr. Wen-Harn Pan)
Common and Ethnic-Specific Genetic Determinants of Hemoglobin Concentration between Taiwanese Han Chinese and European Whites: Findings from Comparative Two-Stage Genome-Wide Association Studies. Timoteo VJ, Chiang KM, Yang HC, Pan WH. J Nutr Biochem. 2022 Aug 11:109126. doi: 10.1016/j.jnutbio.2022.109126. Online ahead of print. PMID: 35964923 -
Binay Kumar Sahoo 沙比內 (Advisor: Dr. Ruey-Bing Yang)
Signal peptide-CUB-EGF-like repeat-containing protein 1-promoted FLT3 signaling is critical for the initiation and maintenance of MLL-rearranged acute leukemia. Sahoo BK, Lin YC, Tu CF, Lin CC, Liao WJ, Li FA, Li LH, Mou KY, Roffler SR, Wang SP, Yeh CT, Yao CY, Hou HA, Chou WC, Tien HF, Yang RB. Haematologica. 2022 Aug 25. doi: 10.3324/haematol.2022.281151. Online ahead of print. PMID: 36005562 -
Afeez Adekunle Ishola 艾菲士 (Advisor: Dr. Shih-Hwa Chiou)
Oncogenic circRNA C190 Promotes Non-Small Cell Lung Cancer via Modulation of the EGFR/ERK Pathway. Ishola AA, Chien CS, Yang YP, Chien Y, Yarmishyn AA, Tsai PH, Chen JC, Hsu PK, Luo YH, Chen YM, Liang KH, Lan YT, Huo TI, Ma HI, Chen MT, Wang ML, Chiou SH. Cancer Res. 2022 Jan 1;82(1):75-89. doi: 10.1158/0008-5472.CAN-21-1473. Epub 2021 Nov 9. PMID: 34753774
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Yan-Hua Lee 李晏嬅 (Advisor: Dr. Yijuang Chern)
A PIAS1 Protective Variant S510G Delays polyQ Disease Onset by Modifying Protein Homeostasis. Lee YH, Tsai YS, Chang CC, Ho CC, Shih HM, Chen HM, Lai HL, Lee CW, Lee YC, Liao YC, Yang UC, Cheng TH, Chern Y, Soong BW. Mov Disord. 2021 Dec 23. doi: 10.1002/mds.28896. Online ahead of print. PMID: 34951052 -
Tzu-Han Lo 駱子翰 (Advisor: Dr. Fu-Tong Liu)
Galectin-3 promotes noncanonical inflammasome activation through intracellular binding to lipopolysaccharide glycans. Lo TH, Chen HL, Yao CI, Weng IC, Li CS, Huang CC, Chen NJ, Lin CH, Liu FT. Proc Natl Acad Sci U S A. 2021 Jul 27;118(30):e2026246118. doi: 10.1073/pnas.2026246118. PMID: 34301890
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Saborni Chattopadhyay 莎柏妮 (Advisor: Dr. Che-Ming Hu)
Nanomedicinal delivery of stimulator of interferon genes agonists: recent advances in virus vaccination. Chattopadhyay S, Hu CJ. Nanomedicine (Lond). 2020 Dec;15(29):2883-2894. doi: 10.2217/nnm-2020-0269. Epub 2020 Nov 30. PMID: 33252301 -
Cheng-Hao Liu 劉程豪 (Advisor: Dr. Kurt Yun Mou)
Combining Proximity Labeling and Cross-Linking Mass Spectrometry for Proteomic Dissection of Nuclear Envelope Interactome. Liu CH, Chien MJ, Chang YC, Cheng YH, Li FA, Mou KY. J Proteome Res. 2020 Mar 6;19(3):1109-1118. doi: 10.1021/acs.jproteome.9b00609. Epub 2020 Feb 7. PMID: 31989825 -
Saborni Chattopadhyay 莎柏妮 (Advisor: Dr. Che-Ming Jack Hu )
Synthetic Immunogenic Cell Death Mediated by Intracellular Delivery of STING Agonist Nanoshells Enhances Anticancer Chemo-immunotherapy. Chattopadhyay S, Liu YH, Fang ZS, Lin CL, Lin JC, Yao BY, Hu CJ. Nano Lett. 2020 Apr 8;20(4):2246-2256. doi: 10.1021/acs.nanolett.9b04094. Epub 2020 Mar 17. PMID: 32160474 -
Rajeev Vikram 瑞奇 (Advisor: Dr. Chen-Yang Shen )
Tumorigenic and Metastatic Role of CD44-/low/CD24-/low Cells in Luminal Breast Cancer. Vikram R, Chou WC, Hung SC, Shen CY. Cancers (Basel). 2020 May 14;12(5):1239. doi: 10.3390/cancers12051239. PMID: 32423137 -
Mei-Han Kao 高媺涵 (Advisor: Dr. Teng-Nan Lin)
Clinacanthus nutans Mitigates Neuronal Death and Reduces Ischemic Brain Injury: Role of NF-κB-driven IL-1β Transcription. Kao MH, Wu JS, Cheung WM, Chen JJ, Sun GY, Ong WY, Herr DR, Lin TN. Neuromolecular Med. 2021 Mar;23(1):199-210. doi: 10.1007/s12017-020-08618-y. Epub 2020 Oct 6. PMID: 33025396 -
Musin Kelel Abas 柯沐新 (Advisor: Dr. Yungling Leo Lee )
FUT8 Remodeling of EGFR Regulates Epidermal Keratinocyte Proliferation during Psoriasis Development. Kelel M, Yang RB, Tsai TF, Liang PH, Wu FY, Huang YT, Yang MF, Hsiao YP, Wang LF, Tu CF, Liu FT, Lee YL. J Invest Dermatol. 2021 Mar;141(3):512-522. doi: 10.1016/j.jid.2020.07.030. Epub 2020 Sep 2. PMID: 32888953 -
Cheng-Hao Liu 劉程豪 (Advisor: Dr. Kurt Yun Mou)
Treatment of murine colitis by Saccharomyces boulardii secreting atrial natriuretic peptide. Liu CH, Chang JH, Chang YC, Mou KY. J Mol Med (Berl). 2020 Dec;98(12):1675-1687. doi: 10.1007/s00109-020-01987-8. Epub 2020 Oct 6. PMID: 33025105 -
Yen Lurk Lee 李延樂 (Advisor: Dr. Yi-Shuian Huang )
CMTR1-Catalyzed 2'-O-Ribose Methylation Controls Neuronal Development by Regulating Camk2α Expression Independent of RIG-I Signaling. Lee YL, Kung FC, Lin CH, Huang YS. Cell Rep. 2020 Oct 20;33(3):108269. doi: 10.1016/j.celrep.2020.108269. PMID: 33086056 -
Saborni Chattopadhyay 莎柏妮 (Advisor: Dr. Che-Ming Jack Hu )
Synthetic Immunogenic Cell Death Mediated by Intracellular Delivery of STING Agonist Nanoshells Enhances Anticancer Chemo-immunotherapy. Chattopadhyay S, Liu YH, Fang ZS, Lin CL, Lin JC, Yao BY, Hu CJ. Nano Lett. 2020 Apr 8;20(4):2246-2256. doi: 10.1021/acs.nanolett.9b04094. Epub 2020 Mar 17. PMID: 32160474 -
Prabha Regmi 白莉敏 (Advisor: Dr. Te-Chang Lee )
SAHA Overcomes 5-FU Resistance in IFIT2-Depleted Oral Squamous Cell Carcinoma Cells. Regmi P, Lai KC, Liu CJ, Lee TC. Cancers (Basel). 2020 Nov 26;12(12):3527. doi: 10.3390/cancers12123527. PMID: 33256074
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Ya-Ting Chang 張雅婷 (Advisor: Dr. Chien-Chang Chen)
Anterior nucleus of paraventricular thalamus mediates chronic mechanical hyperalgesia. Chang YT, Chen WH, Shih HC, Min MY, Shyu BC, Chen CC. Pain. 2019 May;160(5):1208-1223. doi: 10.1097/j.pain.0000000000001497. PMID: 31009420 -
Tsung-Hsi Tu 杜宗熹 (Advisor: Dr. Henrich Cheng)
Characterizing the Neuroprotective Effects of S/B Remedy (Scutellaria baicalensis Georgi and Bupleurum scorzonerifolfium Willd) in Spinal Cord Injury. Tu TH, Liou DY, Lin DY, Yang HC, Chen CJ, Huang MC, Huang WC, Tsai MJ, Cheng H. Molecules. 2019 May 16;24(10):1885. doi: 10.3390/molecules24101885. PMID: 31100896 -
Mahantesh Biradar 馬翰德 (Advisor: Dr. Wen-Harn Pan)
The causal role of elevated uric acid and waist circumference on the risk of metabolic syndrome components. Biradar MI, Chiang KM, Yang HC, Huang YT, Pan WH. Int J Obes (Lond). 2020 Apr;44(4):865-874. doi: 10.1038/s41366-019-0487-9. Epub 2019 Nov 21. PMID: 31754239 -
Min Hsun Kuo 郭旻勳 (Advisor: Dr. Hsueh-Te Lee)
Astaxanthin Ameliorates Ischemic-Hypoxic-Induced Neurotrophin Receptor p75 Upregulation in the Endothelial Cells of Neonatal Mouse Brains. Kuo MH, Lee HF, Tu YF, Lin LH, Cheng YY, Lee HT. Int J Mol Sci. 2019 Dec 6;20(24):6168. doi: 10.3390/ijms20246168. PMID: 31817750 -
Tien-Ching Chang 張恬菁 (Advisor: Dr. Steve Roffler)
Both IgM and IgG Antibodies Against Polyethylene Glycol Can Alter the Biological Activity of Methoxy Polyethylene Glycol-Epoetin Beta in Mice. Chang TC, Chen BM, Lin WW, Yu PH, Chiu YW, Chen YT, Wu JY, Cheng TL, Hwang DY, Roffler AS. Pharmaceutics. 2019 Dec 21;12(1):15. doi: 10.3390/pharmaceutics12010015. PMID: 31877813 -
Min Hsun Kuo 郭旻勳 (Advisor: Dr. Hsueh-Te Lee)
Glucose Transporter 3 is Essential for the Survival of Breast Cancer Cells in the Brain. Kuo MH, Chang WW, Yeh BW, Chu YS, Lee YC, Lee HT. Cells. 2019 Dec 4;8(12):1568. doi: 10.3390/cells8121568. PMID: 31817208 -
Chien Hui Lo 羅芊卉 (Advisor: Dr. Won-Jing Wang)
Phosphorylation of CEP83 by TTBK2 is necessary for cilia initiation. Lo CH, Lin IH, Yang TT, Huang YC, Tanos BE, Chou PC, Chang CW, Tsay YG, Liao JC, Wang WJ. J Cell Biol. 2019 Oct 7;218(10):3489-3505. doi: 10.1083/jcb.201811142. Epub 2019 Aug 27. PMID: 31455668 -
Chia Hsiang Chang 張家祥 (Advisor: Dr. Jin-Wu Tsai)
Atoh1 Controls Primary Cilia Formation to Allow for SHH-Triggered Granule Neuron Progenitor Proliferation. Chang CH, Zanini M, Shirvani H, Cheng JS, Yu H, Feng CH, Mercier AL, Hung SY, Forget A, Wang CH, Cigna SM, Lu IL, Chen WY, Leboucher S, Wang WJ, Ruat M, Spassky N, Tsai JW, Ayrault O. Dev Cell. 2019 Jan 28;48(2):184-199.e5. doi: 10.1016/j.devcel.2018.12.017. PMID: 30695697 -
Oi Kuan Choong 鍾愛君 (Advisor: Dr. Patrick C.H. Hsieh)
Hypoxia-induced H19/YB-1 cascade modulates cardiac remodeling after infarction. Choong OK, Chen CY, Zhang J, Lin JH, Lin PJ, Ruan SC, Kamp TJ, Hsieh PCH. Theranostics. 2019 Aug 21;9(22):6550-6567. doi: 10.7150/thno.35218. eCollection 2019. PMID: 31588235 -
Hsiang-Chi Huang 黃湘琦 (Advisor: Dr. Reiji Kannagi)
Epigenetic silencing of the synthesis of immunosuppressive Siglec ligand glycans by NF-κB/EZH2/YY1 axis in early-stage colon cancers. Huang HC, Chao CC, Wu PH, Chung HY, Lee HY, Suen CS, Hwang MJ, Cai BH, Kannagi R. Biochim Biophys Acta Gene Regul Mech. 2019 Feb;1862(2):173-183. doi: 10.1016/j.bbagrm.2019.01.002. Epub 2019 Feb 1. PMID: 30716533 -
Meng Syuan Lin 林孟璇 (Advisor: Dr. Yijuang Chern)
Degeneration of ipRGCs in Mouse Models of Huntington's Disease Disrupts Non-Image-Forming Behaviors Before Motor Impairment. Lin MS, Liao PY, Chen HM, Chang CP, Chen SK, Chern Y. J Neurosci. 2019 Feb 20;39(8):1505-1524. doi: 10.1523/JNEUROSCI.0571-18.2018. Epub 2018 Dec 26. PMID: 30587542 -
Vijaya Kumar Pidugu 韋加亞 (Advisor: Dr. Te-Chang Lee)
IFIT1 and IFIT3 promote oral squamous cell carcinoma metastasis and contribute to the anti-tumor effect of gefitinib via enhancing p-EGFR recycling. Pidugu VK, Wu MM, Yen AH, Pidugu HB, Chang KW, Liu CJ, Lee TC. Oncogene. 2019 Apr;38(17):3232-3247. doi: 10.1038/s41388-018-0662-9. Epub 2019 Jan 9. PMID: 30626937 -
Jian Jing Siew 蕭建靖 (Advisor: Dr. Yijuang Chern)
Galectin-3 is required for the microglia-mediated brain inflammation in a model of Huntington's disease. Siew JJ, Chen HM, Chen HY, Chen HL, Chen CM, Soong BW, Wu YR, Chang CP, Chan YC, Lin CH, Liu FT, Chern Y. Nat Commun. 2019 Aug 2;10(1):3473. doi: 10.1038/s41467-019-11441-0. PMID: 31375685 -
Yi-Hsiu Wu 吳逸修 (Advisor: Dr. Ya-Jen Chang)
Pulmonary IL-33 orchestrates innate immune cells to mediate respiratory syncytial virus-evoked airway hyperreactivity and eosinophilia. Wu YH, Lai AC, Chi PY, Thio CL, Chen WY, Tsai CH, Lee YL, Lukacs NW, Chang YJ. Allergy. 2020 Apr;75(4):818-830. doi: 10.1111/all.14091. Epub 2019 Nov 12. PMID: 31622507
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Doaa Glal Mohamed Abozeid 高荳 (Advisor: Dr. Jr-Wen Shui)
ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases. Glal D, Sudhakar JN, Lu HH, Liu MC, Chiang HY, Liu YC, Cheng CF, Shui JW. Front Immunol. 2018 Nov 5;9:2522. doi: 10.3389/fimmu.2018.02522. eCollection 2018. PMID: 30455690 -
Chih-Chan Lee 李志展 (Advisor: Dr. Muh-Hwa Yang)
Macrophage-secreted interleukin-35 regulates cancer cell plasticity to facilitate metastatic colonization. Lee CC, Lin JC, Hwang WL, Kuo YJ, Chen HK, Tai SK, Lin CC, Yang MH. Nat Commun. 2018 Sep 14;9(1):3763. doi: 10.1038/s41467-018-06268-0. PMID: 30218063 [PDF] -
Yu-Chia Chuang 莊育嘉 (Advisor: Dr. Chih-Cheng Chen)
Involvement of advillin in somatosensory neuron subtype-specific axon regeneration and neuropathic pain. Chuang YC, Lee CH, Sun WH, Chen CC. Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8557-E8566. doi: 10.1073/pnas.1716470115. Epub 2018 Aug 20. PMID: 30126982 [PDF] -
Christina Li Ping Thio 張麗萍 (Advisor: Dr. Ya-Jen Chang)
Regulation of type 2 innate lymphoid cell-dependent airway hyperreactivity by butyrate. Thio CL, Chi PY, Lai AC, Chang YJ. J Allergy Clin Immunol. 2018 Dec;142(6):1867-1883.e12. doi: 10.1016/j.jaci.2018.02.032. Epub 2018 Mar 6. PMID: 29522844 [PDF] -
Talal Salem Al-Qaisi 安奎道 (Advisor: Dr. Steve R. Roffler)
Transient AID expression for in situ mutagenesis with improved cellular fitness. Al-Qaisi TS, Su YC, Roffler SR. Sci Rep. 2018 Jun 20;8(1):9413. doi: 10.1038/s41598-018-27717-2. PMID: 29925928 [PDF] -
Dhananjaya D 何安亞 (Advisor: Dr. Woan-Yuh Tarn)
RBM4 Modulates Radial Migration via Alternative Splicing of Dab1 during Cortex Development. D D, Hung KY, Tarn WY. Mol Cell Biol. 2018 May 29;38(12):e00007-18. doi: 10.1128/MCB.00007-18. Print 2018 Jun 15. PMID: 29581187 [PDF] -
Pierre-Alain Burnouf 白宸睿 (Advisor: Dr. Steve R. Roffler)
Reversible glycosidic switch for secure delivery of molecular nanocargos. Burnouf PA, Leu YL, Su YC, Wu K, Lin WC, Roffler SR. Nat Commun. 2018 May 10;9(1):1843. doi: 10.1038/s41467-018-04225-5. PMID: 29748577 [PDF] -
Mohammad Ameen Alaghbar 歐默漢 (Advisor: Dr. Steve R. Roffler)
High-Affinity Ligands Can Trigger T Cell Receptor Signaling Without CD45 Segregation. Al-Aghbar MA, Chu YS, Chen BM, Roffler SR. Front Immunol. 2018 Apr 9;9:713. doi: 10.3389/fimmu.2018.00713. eCollection 2018. PMID: 29686683 [PDF]
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Ching-Chun Yang 楊清淳 (Advisor: Dr. Chiaho Shih)
A Homokaryon Assay for Nucleocytoplasmic Shuttling Activity of HBV Core Protein. Yang CC, Li HC, Shih C. Methods Mol Biol. 2017;1540:53-58. doi: 10.1007/978-1-4939-6700-1_5. PMID: 27975307 -
Wen-Hsin Lu 呂文心 (Advisor: Dr. Yi-Shuian Huang)
CPEB2 Activates GRASP1 mRNA Translation and Promotes AMPA Receptor Surface Expression, Long-Term Potentiation, and Memory. Lu WH, Yeh NH, Huang YS. Cell Rep. 2017 Nov 14;21(7):1783-1794. doi: 10.1016/j.celrep.2017.10.073. PMID: 29141213 [PDF] -
Gansukh Choijilsuren 札蘇光士 (Advisor: Dr. Chiaho Shih)
Heparin at physiological concentration can enhance PEG-free in vitro infection with human hepatitis B virus. Choijilsuren G, Jhou RS, Chou SF, Chang CJ, Yang HI, Chen YY, Chuang WL, Yu ML, Shih C. Sci Rep. 2017 Oct 31;7(1):14461. doi: 10.1038/s41598-017-14573-9. PMID: 29089529 [PDF] -
Ya-Lin Lin 林雅琳 (Advisor: Dr. Fang Liao)
CCR6 Deficiency Impairs IgA Production and Dysregulates Antimicrobial Peptide Production, Altering the Intestinal Flora. Lin YL, Ip PP, Liao F. Front Immunol. 2017 Jul 11;8:805. doi: 10.3389/fimmu.2017.00805. eCollection 2017. PMID: 28744287 [PDF] -
Mohammad Ameen Alaghbar 歐默漢 (Advisor: Dr. Steve R. Roffler)
The Affinity of Elongated Membrane-Tethered Ligands Determines Potency of T Cell Receptor Triggering. Chen BM*, Al-Aghbar MA*, Lee CH, Chang TC, Su YC, Li YC, Chang SE, Chen CC, Chung TH, Liao YC, Lee CH, Roffler SR. Front Immunol. 2017 Jul 10;8:793. doi: 10.3389/fimmu.2017.00793. eCollection 2017. PMID: 28740495 [PDF] (*contributed equally) -
Chia-Chen Lu 呂佳臻 (Advisor: Dr. Woan-Yuh Tarn)
Y14 governs p53 expression and modulates DNA damage sensitivity. Lu CC, Lee CC, Tseng CT, Tarn WY. Sci Rep. 2017 Mar 31;7:45558. doi: 10.1038/srep45558. PMID: 28361991 [PDF] -
Jui-Hao Lee 李睿豪 (Advisor: Dr. Chi-Hung Lin)
Lipid raft-associated stomatin enhances cell fusion. Lee JH, Hsieh CF, Liu HW, Chen CY, Wu SC, Chen TW, Hsu CS, Liao YH, Yang CY, Shyu JF, Fischer WB, Lin CH. FASEB J. 2017 Jan;31(1):47-59. doi: 10.1096/fj.201600643R. Epub 2016 Sep 23. PMID: 27663861 [PDF]
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Pei-Yi Su 蘇倍儀 (Advisor: Dr. Chiaho Shih)
HBV maintains electrostatic homeostasis by modulating negative charges from phosphoserine and encapsidated nucleic acids. Su PY, Yang CJ, Chu TH, Chang CH, Chiang C, Tang FM, Lee CY, Shih C. Sci Rep. 2016 Dec 13;6:38959. doi: 10.1038/srep38959. PMID: 27958343 [PDF] -
Marilyn Rimando 雷瑪琳 (Advisor: Dr. Oscar Kuang-Sheng Lee)
Glucocorticoid receptor and Histone deacetylase 6 mediate the differential effect of dexamethasone during osteogenesis of mesenchymal stromal cells (MSCs). Rimando MG, Wu HH, Liu YA, Lee CW, Kuo SW, Lo YP, Tseng KF, Liu YS, Lee OK. Sci Rep. 2016 Nov 30;6:37371. doi: 10.1038/srep37371. PMID: 27901049 [PDF] -
An-Ting Liou 劉安庭 (Advisor: Dr. Chiaho Shih)
A new animal model containing human SCARB2 and lacking stat-1 is highly susceptible to EV71. Liou AT, Wu SY, Liao CC, Chang YS, Chang CS, Shih C. Sci Rep. 2016 Aug 8;6:31151. doi: 10.1038/srep31151. PMID: 27499235 [PDF] -
Nana Hsiang-Hua Wang 王襄華 (Advisor: Dr. Yuan-Tsong Chen)
Homozygosity Mapping and Whole-Genome Sequencing Links a Missense Mutation in POMGNT1 to Autosomal Recessive Retinitis Pigmentosa. Wang NH, Chen SJ, Yang CF, Chen HW, Chuang HP, Lu YH, Chen CH, Wu JY, Niu DM, Chen YT. Invest Ophthalmol Vis Sci. 2016 Jul 1;57(8):3601-9. doi: 10.1167/iovs.16-19463. PMID: 27391550 [PDF] -
Tzu-Po Chuang 莊諮博 (Advisor: Dr. Yuan-Tsong Chen & Dr. Ling-Hui Li)
Over-expression of AURKA, SKA3 and DSN1 contributes to colorectal adenoma to carcinoma progression. Chuang TP, Wang JY, Jao SW, Wu CC, Chen JH, Hsiao KH, Lin CY, Chen SH, Su SY, Chen YJ, Chen YT, Wu DC, Li LH. Oncotarget. 2016 Jul 19;7(29):45803-45818. doi: 10.18632/oncotarget.9960. PMID: 27329586 [PDF] -
Wei-Sheng Sun 孫維聲 (Advisor: Dr. Wan-Jr Syu)
Expression Regulation of Polycistronic lee3 Genes of Enterohaemorrhagic Escherichia coli. Sun WS, Chen JW, Wu YC, Tsai HY, Kuo YL, Syu WJ. PLoS One. 2016 May 16;11(5):e0155578. doi: 10.1371/journal.pone.0155578. eCollection 2016. PMID: 27182989 [PDF] -
Ching-Pang Chang 張敬邦 (Advisor: Dr. Yijuang Chern)
Type VI adenylyl cyclase negatively regulates GluN2B-mediated LTD and spatial reversal learning. Chang CP, Lee CT, Hou WH, Lin MS, Lai HL, Chien CL, Chang C, Cheng PL, Lien CC, Chern Y. Sci Rep. 2016 Mar 2;6:22529. doi: 10.1038/srep22529. PMID: 26932446 [PDF]
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Chia-Sui Sun 孫嘉穗 (Advisor: Dr. Yijuang Chern and Dr. Joseph Jen-Tse Huang)
Conformational switch of polyglutamine-expanded huntingtin into benign aggregates leads to neuroprotective effect. Sun CS, Lee CC, Li YN, Yao-Chen Yang S, Lin CH, Chang YC, Liu PF, He RY, Wang CH, Chen W, Chern Y, Jen-Tse Huang J. Sci Rep. 2015 Oct 9;5:14992. doi: 10.1038/srep14992. PMID: 26450664 [PDF] -
Ai-Chung Mar 馬璦中 (Advisor: Dr. Te-Chang Lee)
Interleukin-1 Receptor Type 2 Acts with c-Fos to Enhance the Expression of Interleukin-6 and Vascular Endothelial Growth Factor A in Colon Cancer Cells and Induce Angiogenesis. Mar AC, Chu CH, Lee HJ, Chien CW, Cheng JJ, Yang SH, Jiang JK, Lee TC. J Biol Chem. 2015 Sep 4;290(36):22212-24. doi: 10.1074/jbc.M115.644823. Epub 2015 Jul 24. PMID: 26209639 [PDF] -
Ying-Chi Chao 趙英淇 (Advisor: Dr. Ruey-Bing Yang)
Receptor guanylyl cyclase-G is a novel thermosensory protein activated by cool temperatures. Chao YC, Chen CC, Lin YC, Breer H, Fleischer J, Yang RB. EMBO J. 2015 Feb 3;34(3):294-306. doi: 10.15252/embj.201489652. Epub 2014 Dec 1. PMID: 25452496 [PDF] -
Pei-Ying Lin 林佩瑩 (Advisor: Dr. Pan-Cher Yang and Dr. Konan Peck)
Association Between Parkinson Disease and Risk of Cancer in Taiwan. Lin PY, Chang SN, Hsiao TH, Huang BT, Lin CH, Yang PC. JAMA Oncol. 2015 Aug;1(5):633-40. doi: 10.1001/jamaoncol.2015.1752. PMID: 26181771 [PDF] -
Hsin-Yi Tung 童馨儀 (Advisor: Dr. Steve R. Roffler)
Selective Delivery of PEGylated Compounds to Tumor Cells by Anti-PEG Hybrid Antibodies. Tung HY, Su YC, Chen BM, Burnouf PA, Huang WC, Chuang KH, Yan YT, Cheng TL, Roffler SR. Mol Cancer Ther. 2015 Jun;14(6):1317-26. doi: 10.1158/1535-7163.MCT-15-0151. Epub 2015 Apr 7. PMID: 25852063 [PDF] -
Yogy Simanjuntak 史曼均 (Advisor: Dr. Yi-Ling Lin)
Repurposing of prochlorperazine for use against dengue virus infection. Simanjuntak Y, Liang JJ, Lee YL, Lin YL. J Infect Dis. 2015 Feb 1;211(3):394-404. doi: 10.1093/infdis/jiu377. Epub 2014 Jul 14. PMID: 25028694 [PDF] -
Wen-Chuan Shen 沈文荃 (Advisor: Dr. Pang-Hsien Tu and Dr. Yijuang Chern)
Mutations in the ubiquitin-binding domain of OPTN/optineurin interfere with autophagy-mediated degradation of misfolded proteins by a dominant-negative mechanism. Shen WC, Li HY, Chen GC, Chern Y, Tu PH. Autophagy. 2015 Apr 3;11(4):685-700. doi: 10.4161/auto.36098. PMID: 25484089 [PDF] -
Irfan Naseem Bandey 潘爾納 (Advisor: Dr. Pang-Hsien Tu)
Progranulin promotes Temozolomide resistance of glioblastoma by orchestrating DNA repair and tumor stemness. Bandey I, Chiou SH, Huang AP, Tsai JC, Tu PH. Oncogene. 2015 Apr 2;34(14):1853-64. doi: 10.1038/onc.2014.92. Epub 2014 May 5. PMID: 24793792 [PDF]
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Chia-Sui Sun 孫嘉穗 (Advisor: Joseph Jen-Tse Huang)
The influence of pathological mutations and proline substitutions in TDP-43 glycine-rich peptides on its amyloid properties and cellular toxicity. Sun CS, Wang CY, Chen BP, He RY, Liu GC, Wang CH, Chen W, Chern Y, Huang JJ. PLoS One. 2014 Aug 4;9(8):e103644. doi: 10.1371/journal.pone.0103644. eCollection 2014. PMID: 25090004 -
Ching-Chun Yang 楊清淳 (Advisor: Chiaho Shih)
Nuclear export of human hepatitis B virus core protein and pregenomic RNA depends on the cellular NXF1-p15 machinery. Yang CC, Huang EY, Li HC, Su PY, Shih C. PLoS One. 2014 Oct 31;9(10):e106683. doi: 10.1371/journal.pone.0106683. eCollection 2014. PMID: 25360769 -
Wei-Ting Chen 陳暐婷 (Advisor: Dr. Irene Han-Juo Cheng)
G206D Mutation of Presenilin-1 Reduces Pen2 Interaction, Increases Aβ42/Aβ40 Ratio and Elevates ER Ca(2+) Accumulation. Chen WT, Hsieh YF, Huang YJ, Lin CC, Lin YT, Liu YC, Lien CC, Cheng IH. Mol Neurobiol. 2015 Dec;52(3):1835-1849. doi: 10.1007/s12035-014-8969-1. Epub 2014 Nov 15. PMID: 25394380 [PDF] -
Kai-Ting Chen 陳凱婷 (Advisor: Dr. Hsei-Wei Wang)
Liver X receptor α (LXRα/NR1H3) regulates differentiation of hepatocyte-like cells via reciprocal regulation of HNF4α. Chen KT, Pernelle K, Tsai YH, Wu YH, Hsieh JY, Liao KH, Guguen-Guillouzo C, Wang HW. J Hepatol. 2014 Dec;61(6):1276-86. doi: 10.1016/j.jhep.2014.07.025. Epub 2014 Jul 27. PMID: 25073010 [PDF] -
Cheng-Fen Tu 凃瀞芬 (Advisor: Dr. Ruey-Bing Ray Yang)
SCUBE3 (signal peptide-CUB-EGF domain-containing protein 3) modulates fibroblast growth factor signaling during fast muscle development. Tu CF, Tsao KC, Lee SJ, Yang RB. J Biol Chem. 2014 Jul 4;289(27):18928-42. doi: 10.1074/jbc.M114.551929. Epub 2014 May 21. PMID: 24849601 [PDF] -
Wei-Yun Lai 賴薇云 (Advisor: Dr. Pan-Cher Yang and Dr. Konan Peck)
Overcoming EGFR T790M-based Tyrosine Kinase Inhibitor Resistance with an Allele-specific DNAzyme. Lai WY, Chen CY, Yang SC, Wu JY, Chang CJ, Yang PC, Peck K. Mol Ther Nucleic Acids. 2014 Mar 4;3(3):e150. doi: 10.1038/mtna.2014.3. PMID: 24594844 [PDF]
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Yi-Chih Wu 吳宜之 (Advisor: Dr. Yijuang Chern)
A novel Gαs-binding protein, Gas-2 like 2, facilitates the signaling of the A2A adenosine receptor. Wu YC, Lai HL, Chang WC, Lin JT, Liu YJ, Chern Y. Biochim Biophys Acta. 2013 Dec;1833(12):3145-3154. doi: 10.1016/j.bbamcr.2013.08.009. Epub 2013 Aug 27. PMID: 23994616 [PDF] -
Yu-Wang Chang 張裕旺 (Advisor: Dr. Chien-Chang Chen)
Quantitative phosphoproteomic study of pressure-overloaded mouse heart reveals dynamin-related protein 1 as a modulator of cardiac hypertrophy. Chang YW, Chang YT, Wang Q, Lin JJ, Chen YJ, Chen CC. Mol Cell Proteomics. 2013 Nov;12(11):3094-107. doi: 10.1074/mcp.M113.027649. Epub 2013 Jul 23. PMID: 23882026 [PDF] -
Shao-Chun Hsu 許紹君 (Advisor: Dr. Chien-Chang Chen)
Early growth response 1 is an early signal inducing Cav3.2 T-type calcium channels during cardiac hypertrophy. Hsu SC, Chang YT, Chen CC. Cardiovasc Res. 2013 Nov 1;100(2):222-30. doi: 10.1093/cvr/cvt190. Epub 2013 Aug 8. PMID: 23929524 [PDF] -
Cheng-Pu Sun 孫承溥 (Advisor: Dr. Mi-Hua Tao)
Studies of efficacy and liver toxicity related to adeno-associated virus-mediated RNA interference. Sun CP, Wu TH, Chen CC, Wu PY, Shih YM, Tsuneyama K, Tao MH. Hum Gene Ther. 2013 Aug;24(8):739-50. doi: 10.1089/hum.2012.239. PMID: 23829557 [PDF] -
Hsiao-Hui Tseng 曾曉慧 (Advisor: Dr. Danny Ling Wang)
SIRT3 deacetylates FOXO3 to protect mitochondria against oxidative damage. Tseng AH, Shieh SS, Wang DL. Free Radic Biol Med. 2013 Oct;63:222-34. doi: 10.1016/j.freeradbiomed.2013.05.002. Epub 2013 May 7. PMID: 23665396 [PDF]
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Wei-Chih Yang 楊偉志 (Advisor: Dr. Hsiu-Ming Shih)
The deubiquitinating enzyme USP37 regulates the oncogenic fusion protein PLZF/RARA stability. Yang WC, Shih HM. Oncogene. 2013 Oct 24;32(43):5167-75. doi: 10.1038/onc.2012.537. Epub 2012 Dec 3. PMID: 23208507 [PDF] -
Wen-Yu Pan 潘玟伃 (Advisor: Dr. Mi-Hua Tao)
Cancer immunotherapy using a membrane-bound interleukin-12 with B7-1 transmembrane and cytoplasmic domains. Pan WY, Lo CH, Chen CC, Wu PY, Roffler SR, Shyue SK, Tao MH. Mol Ther. 2012 May;20(5):927-37. doi: 10.1038/mt.2012.10. Epub 2012 Feb 14. PMID: 22334018 [PDF] -
Chun-Yu Wei 魏淳郁 (Advisor: Dr. Yuan-Tsong Chen and Dr. Shuen-Iu Hung)
Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome. Wei CY, Chung WH, Huang HW, Chen YT, Hung SI. J Allergy Clin Immunol. 2012 Jun;129(6):1562-9.e5. doi: 10.1016/j.jaci.2011.12.990. Epub 2012 Feb 8. PMID: 22322005 [PDF] -
Chia-Ching Lin 林家靖 (Advisor: Dr. Chih-Cheng Chen)
An antinociceptive role for substance P in acid-induced chronic muscle pain. Lin CC, Chen WN, Chen CJ, Lin YW, Zimmer A, Chen CC. Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):E76-83. doi: 10.1073/pnas.1108903108. Epub 2011 Nov 14. PMID: 22084095 [PDF] -
Kumar Sanjiv 薩克瑪 (Advisor: Dr. Lee, Te-Chang)
The novel DNA alkylating agent BO-1090 suppresses the growth of human oral cavity cancer in xenografted and orthotopic mouse models. Sanjiv K, Su TL, Suman S, Kakadiya R, Lai TC, Wang HY, Hsiao M, Lee TC. Int J Cancer. 2012 Mar 15;130(6):1440-50. doi: 10.1002/ijc.26142. Epub 2011 Jul 21. PMID: 21500194 [PDF]
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Wei-Lun Hwang 黃尉倫 (Advisor: Dr. Hsei-Wei Wang)
SNAIL regulates interleukin-8 expression, stem cell-like activity, and tumorigenicity of human colorectal carcinoma cells. Hwang WL, Yang MH, Tsai ML, Lan HY, Su SH, Chang SC, Teng HW, Yang SH, Lan YT, Chiou SH, Wang HW. Gastroenterology. 2011 Jul;141(1):279-91, 291.e1-5. doi: 10.1053/j.gastro.2011.04.008. Epub 2011 Apr 16. PMID: 21640118 [PDF] -
Huei-Ying Li 李慧瑛 (Advisor: Dr. Pang-Hsien Tu)
Hyperphosphorylation as a defense mechanism to reduce TDP-43 aggregation. Li HY, Yeh PA, Chiu HC, Tang CY, Tu BP. PLoS One. 2011;6(8):e23075. doi: 10.1371/journal.pone.0023075. Epub 2011 Aug 5. PMID: 21850253 [PDF] -
Abd-Al-Ahad nagham George 艾妮荷 (Advisor: Dr. Yuan-Tsong Chen)
Alternative splicing in Acad8 resulting a mitochondrial defect and progressive hepatic steatosis in mice. Sabbagha NG, Kao HJ, Yang CF, Huang CC, Lin WD, Tsai FJ, Chen TH, Tarn WY, Wu JY, Chen YT. Pediatr Res. 2011 Jul;70(1):31-6. doi: 10.1203/PDR.0b013e31821b89ee. PMID: 21659959 [PDF]
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Wen-Hung Chung 鐘文宏 (Advisor: Dr. Yuan-Tsong Chen)
Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis. Chung WH, Hung SI, Yang JY, Su SC, Huang SP, Wei CY, Chin SW, Chiou CC, Chu SC, Ho HC, Yang CH, Lu CF, Wu JY, Liao YD, Chen YT. Nat Med. 2008 Dec;14(12):1343-50. doi: 10.1038/nm.1884. Epub 2008 Nov 23. PMID: 19029983 [PDF]