Dr. Chen, Joanne Jeou-Yuan 張久瑗 博士

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  • Proteoglycan serglycin promotes non-small cell lung cancer cell migration through the interaction of its glycosaminoglycans with CD44
    Journal of Biomedical Science Jan 02, 2020
    Background Serglycin (SRGN), previously recognized as an intracellular proteoglycan involved in the storage processes of secretory granul ......
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  • ITPKA Gene Body Methylation Regulates Gene Expression and Serves as an Early Diagnostic Marker in Lung and Other Cancers
    Journal of Thoracic Oncology May 24, 2016
    Introduction Despite recent advances in cancer therapy, the overall 5-year survival rate of patients with lung cancer remains low. The ......
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  • Serglycin in tumor microenvironment promotes non-small cell lung cancer aggressiveness in a CD44-dependent manner
    Oncogene Nov 07, 2016
    Tumor microenvironment (TME) plays an active role in promoting tumor progression. To further understand the communication between TME and tu ......
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  • Functional assessment of glioma pathogenesis by in vivo multi-parametric magnetic resonance imaging and in vitro analyses
    Scientific Report Jun 01, 2016
    Gliomas are aggressive brain tumors with poor prognosis. In this study, we report a novel approach combining both in vivo multi-pa ......
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  • Loss of PTPRM Associates with the Pathogenic Development of Colorectal Adenoma-Carcinoma Sequence
    Scientific Report Apr 24, 2015
    Identification and functional analysis of genes from genetically altered chromosomal regions would suggest new molecular targets for canc ......
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