Dr. Shih, Hsiu-Ming
施修明 博士
INTRODUCTION
實驗室介紹
HIGHLIGHTS
重要成果
PUBLICATIONS
研究論文
MEMBERS
實驗室成員
JOB
徵人啟事
ALBUM
相簿
HIGHLIGHTS
重要成果
Molecular mechanism of K65 acetylation-induced attenuation of Ubc9 and the NDSM interaction
Scientific Reports, Dec 12, 2017
The negatively charged amino acid-dependent sumoylation motif (NDSM) carries an additional stretch of acidic residues downstream of the cons ......
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Xist reduction in breast cancer upregulates AKT phosphorylation via HDAC3-mediated repression of PHLPP1 expression
Oncotarget, May 27, 2016
Long noncoding RNAs (lncRNAs) dysregulated in cancer potentially play oncogenic or tumor-suppressive roles. While the X inactivate-specific ......
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HIC1 interacts with and modulates the activity of STAT3.
Cell Cycle., Jun 21, 2013
Abstract: HIC1 (hypermethylated in cancer 1) is a tumor suppressor gene, expression of which is frequently suppressed in human cancers. Very ......
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Ubc9 acetylation modulates distinct SUMO target modification and hypoxia response.
EMBO J., Feb 08, 2013
While numerous small ubiquitin-like modifier (SUMO) conjugated substrates have been identified, very little is known about the cellular sign ......
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The deubiquitinating enzyme USP37 regulates the oncogenic fusion protein PLZF/RARA stability.
Oncogene, Dec 03, 2012
Acute promyelocytic leukemia (APL) is predominantly characterized by chromosomal translocations between the retinoic acid receptor, alpha (R ......
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List of Highlights
文件紀錄
Molecular mechanism of K65 acetylation-induced attenuation of Ubc9 and the NDSM interaction
Scientific Reports Dec 12, 2017
Xist reduction in breast cancer upregulates AKT phosphorylation via HDAC3-mediated repression of PHLPP1 expression
Oncotarget May 27, 2016
HIC1 interacts with and modulates the activity of STAT3.
Cell Cycle. Jun 21, 2013
Ubc9 acetylation modulates distinct SUMO target modification and hypoxia response.
EMBO J. Feb 08, 2013
The deubiquitinating enzyme USP37 regulates the oncogenic fusion protein PLZF/RARA stability.
Oncogene Dec 03, 2012
Sumoylation-promoted enterovirus 71 3C degradation correlates with a reduction in viral replication and cell apoptosis
Journal of Biological Chemistry Sep 09, 2011
Structural and Functional Roles of Daxx SIM Phosphorylation in SUMO Paralog-Selective Binding and Apoptosis Modulation.
Molecular Cell May 08, 2011
Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability.
J Cell Biol. Jun 21, 2010
Role of SUMO-Interacting Motif in Daxx SUMO Modification, Subnuclear Localization, and Repression of Sumoylated Transcription Factors.
Molecular Cell Nov 03, 2006
SUMO modification negatively modulates the transcriptional activity of CREB-binding protein via the recruitment of Daxx.
PNAS. Nov 22, 2005
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