Dr. Tang, Tang K. 唐堂 博士

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(invited News and Views article) Centriole biogenesis in multiciliated cells.

Nat Cell Biol., Dec 02, 2013

Centrioles duplicate only once per cell cycle in proliferating cells, whereas in multiciliated cells, hundreds of centrioles form almost simultaneously. The molecular control mechanisms that govern centriole amplification in multiciliated cells are largely unknown. Two studies highlight Deup1 and CCDC78 as key players in this process.

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