Dr. Lim, Carmay 林小喬 博士

Brand

HIGHLIGHT DETAIL
重要成果詳細內容


Ion Selectivity Strategies of Sodium Channel Selectivity Filters.

Acc Chem Res., Oct 24, 2014

Conspectus Sodium ion channels selectively transport Na+ cations across the cell membrane. These integral parts of the cell machinery are implicated in regulating the cardiac, skeletal and smooth muscle contraction, nerve impulses, salt and water homeostasis, as well as pain and taste perception. Their malfunction often results in various channelopathies of the heart, brain, skeletal muscles, and lung; thus, sodium channels are key drug targets for various disorders including cardiac arrhythmias, heart attack, stroke, migraine, epilepsy, pain, cancer, and autoimmune disorders.

Journal Link 期刊連結

List of Highlights
文件紀錄

Top