Dr. Huang, Yi-Shuian 黃怡萱 博士

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CPEB2–eEF2 interaction impedes HIF-1α RNA translation

EMBO J, Dec 09, 2011

Translation of mRNA into protein proceeds in three phases: initiation, elongation, and termination. Regulated translation allows the prompt production of selective proteins in response to physiological needs and is often controlled by sequence-specific RNA-binding proteins that function at initiation. Whether the elongation phase of translation can be modulated individually by trans-acting factors to synthesize polypeptides at variable rates remains to be determined

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