Dr. Lin, Wen-chang 林文昌 博士

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Designating eukaryotic orthology via processed transcription units.

Nucleic Acids Research, Apr 29, 2008

Orthology is a widely used concept in comparative and evolutionary genomics. In addition to prokaryotic orthology, delineating eukaryotic orthology has provided insight into the evolution of higher organisms. Indeed, many eukaryotic ortholog databases have been established for this purpose. However, unlike prokaryotes, alternative splicing (AS) has hampered eukaryotic orthology assignments.

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