Dr. Shieh, Sheau-Yann 謝小燕 博士

Brand

HIGHLIGHT DETAIL
重要成果詳細內容


The cell cycle checkpoint kinase CHK2 mediates DNA damage-induced stabilization of TTK/hMps1.

Oncogene, Jan 19, 2009

Cell cycle progression is monitored constantly to ensure faithful passage of genetic codes and genome stability. We have demonstrated previously that, upon DNA damage, TTK/hMps1 activates the checkpoint kinase CHK2 by phosphorylating CHK2 at Thr68.

Journal Link 期刊連結
Top