Dr. Li, Chia-Wei 's publons link picture

李家偉博士

助研究員
  • 02-2789-9055 (Lab) (Room No: N147)
  • 02-2652-3912 (Office)
  • 02-2782-9224 (Fax)

Specialty:
  • Cancer immunotherapy
  • Antibody discovery
  • Cancer metastasis

Education and Positions:
  • Ph.D. Rutgers University


Highlight Detail
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MET Inhibitors Promote Liver Tumor Evasion of the Immune Response by Stabilizing PDL1

Dr. Li, Chia-Wei
Gastroenterology, May 01, 2019

In HCC, c-MET blockade drives PD-L1 expression and T cell inactivation in immune-competent mice. Thus, anti-PD-1 enhances the efficacy of c-MET blockade in the orthotopic animal model of HCC. Eighty percent of the immunocompetent mice carrying orthotopic liver cancer demonstrated response to the combination.