Dr. Hwang, Ming-Jing 's publons link picture

Dr. Hwang, Ming-Jing

Adjunct Research Fellow
  • 02-27899033 (Lab) (Room No: N121)
  • 02-27887641 (Fax)

Specialty:
  • Bioinformatics
  • Computational Structural/Systems Biology

Education and Positions:
  • Ph.D. University of Pittsburgh


The main focus of our research has been to develop computational strategies and algorithms for analysis, especially on large-scales, of biological data to extract knowledge and generate hypotheses. Over the years we have developed several bioinformatics tools, such as those for comparing protein structures, protein-protein docking, and ligand binding site prediction. We have also developed network-based approaches to study nature’s design of protein architecture and its evolution, and to understand the design principles of biological circuits. In recent years, we have collaborated with physicians using patient data from local hospitals to develop artificial intelligence (AI) tools for medical applications. Two completed projects are: 1) identification of a handful of circulating miRNA as liquid biopsy biomarkers for detecting and classifying six major cancers; 2) electrocardiogram-based detection of cardiac diseases such as arrhythmias and pulmonary hypertension. These AI tools are currently being implemented to test their prediction effectiveness in real-world clinical settings. In the future, we will continue the AI research, on additional diseases such as sleep apnea, and on biomedicine problems such as drug discovery.

Our Team
Team photo

Journal 80 Book 2

  1. Liu Chih-Min, Shih Edward S.C., Chen Jhih-Yu, Huang Chih-Han, Wu I-Chien, Chen Pei-Fen, Higa Satoshi, Yagi Nobumori, Hu Yu-Feng, Hwang Ming-Jing, Chen Shih-Ann Artificial Intelligence-Enabled Electrocardiogram Improves the Diagnosis and Prediction of Mortality in Patients With Pulmonary Hypertension JACC: Asia 2(3), 258-270 (2022) [JCR] [WOS]
  2. Yang Ching-Chun, Chang Chih-Hsu, Chen Heng-Li, Chou Ming-Chieh, Yang Ching-Jen, Jhou Ren-Shiang, Huang Er-Yi, Li Hung-Cheng, Suen Ching-Shu, Hwang Ming-Jing, Shih Chiaho CRM1-spike-mediated nuclear export of hepatitis B virus encapsidated viral RNA Cell Reports 38(10), 110472 (2022) [JCR] [WOS]
  3. Hu Yu-Feng*, Wu Chih-Hsun, Lai Tsung-Ching, Chang Yu-Chan, (Hwang Ming-Jing), Chang Ting-Yung, Weng Ching-Hui, Chang Peter Mu-Hsin, Chen Che-Hong, Mochly-Rosen Daria, Huang Chi-Ying F., Chen Shih-Ann ALDH2 deficiency induces atrial fibrillation through dysregulated cardiac sodium channel and mitochondrial bioenergetics: A multi-omics analysis Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1867(5), 166088 (2021) [JCR] [WOS]
  4. Chang Chih-Shin, Liao Chun-Che, Liou An-Ting, Chou Yi-Chun, Yu Ya-Yen, Lin Chi-Yung, Lin Jen-Shiou, Suen Ching-Shu, (Hwang Ming-Jing), Shih Chiaho* Novel Naturally Occurring Mutations of Enterovirus 71 Associated With Disease Severity Frontiers in Microbiology 11, 610568 (2021) [JCR] [WOS]
  5. Peng Hubert, Chiu Tzu-Yuan, Liang Yu-Jen, Lee Chia-Jen, Liu Chih-Syuan, Suen Ching-Shu, Yen Jeffrey J.-Y., Chen Hung-Ta, (Hwang Ming-Jing), Hussain M Mahmood, Yang Hsin-Chou, Yang-Yen Hsin-Fang PRAP1 is a novel lipid binding protein that promotes lipid absorption by facilitating MTTP-mediated lipid transport Journal of Biological Chemistry 296, 100052 (2021) [JCR] [WOS]
  6. Chang Kuan-Cheng, Hsieh Po-Hsin, Wu Mei-Yao, Wang Yu-Chen, Chen Jan-Yow, Tsai Fuu-Jen, Shih Edward S.C., (Hwang Ming-Jing), Huang Tzung-Chi Usefulness of Machine Learning-Based Detection and Classification of Cardiac Arrhythmias With 12-Lead Electrocardiograms Canadian Journal of Cardiology 37(1), 94-104 (2021) [JCR] [WOS]
  7. Chang Kuan-Cheng*, Hsieh Po-Hsin, Wu Mei-Yao, Wang Yu-Chen, Wei Jung-Ting, Shih Edward S C, (Hwang Ming-Jing), Lin Wan-Ying, Lin Wan-Ting, Lee Kuan-Jung, Wang Ti-Hao Usefulness of multi-labelling artificial intelligence in detecting rhythm disorders and acute ST-elevation myocardial infarction on 12-lead electrocardiogram European Heart Journal - Digital Health 2(2), 299-310 (2021) [JCR] [WOS]
  8. Huang Meng‐Sen, Chang Jen‐Hsuan, Lin Wen‐Ching, Cheng Yu‐Hsiang, Li Fu‐An, Suen Ching‐Shu, (Hwang Ming‐Jing), Chang Chung‐ke, Mou Kurt Yun SLC38A2 Overexpression Induces a Cancer-like Metabolic Profile and Cooperates with SLC1A5 in Pan-cancer Prognosis Chemistry – An Asian Journal 15(22), 3861-3872 (2020-11) [JCR] [WOS]
  9. Sudhakar Janaki N., Lu Hsueh-Han, Chiang Hung-Yu, Suen Ching-Shu, (Hwang Ming-Jing), Wu Sung-Yu, Shen Chia-Ning, Chang Yao-Ming, Li Fu-An, Liu Fu-Tong, Shui Jr-Wen Lumenal Galectin-9-Lamp2 interaction regulates lysosome and autophagy to prevent pathogenesis in the intestine and pancreas Nature Communications 11(1), 4286 (2020-08) [JCR] [WOS]
  10. Chen Tsai-Min, Huang Chih-Han, Shih Edward S.C., Hu Yu-Feng, (Hwang Ming-Jing)* Detection and Classification of Cardiac Arrhythmias by a Challenge-Best Deep Learning Neural Network Model iScience 23(3) ,100886 (2020-03) [JCR] [WOS]

- POSTDOC -
Shih, Edward S.C.
Shih, Edward S.C.
- RESEARCH ASSOCIATES -
Suen, Ching-Shu
Suen, Ching-Shu
- ALUMNI -
Fang, Wei-Quan
Fang, Wei-Quan
Wang, Hsuan-Kai
Wang, Hsuan-Kai
member
Wu, Chih-Hsun
Huang, Chih-Han
Huang, Chih-Han
Chen, Tsai-Min
Chen, Tsai-Min
Chen, Jhih-Yu
Chen, Jhih-Yu
Hsu, Justine
Hsu, Justine
Chen, Jacob
Chen, Jacob
Lin, Po-An
Lin, Po-An
member
Yang, Shu-Yu
Shannon, Brian D.
Shannon, Brian D.