Dr. Chen, Steve S.-L.

Emeritus Research Fellow

Specialty:
  • Retrovirology
  • HCV
  • Virus-host Interactions
  • Virus Assembly and Budding

Education and Positions:
  • Ph.D., Biochemistry,  Purdue University


Journal 74 Book 2

  1. Wong, M.T. and Chen, S.S.* Hepatitis C virus subverts human choline kinase-α to bridge PI4KIIIα and NS5A and upregulates PI4KIIIα activation, thereby promoting the translocation of the ternary complex to the ER for viral replication JOURNAL OF VIROLOGY 91(16), e00355-17 (2017-0-15) [JCR] [WOS]
  2. Wong, M.T. and Chen, S.S.* Human choline kinase-alpha promotes hepatitis C virus RNA replication through modulating membranous viral replication complex formation JOURNAL OF VIROLOGY 90(20), 9075-9095 (2016-10) [JCR] [WOS]
  3. Chong, M.W., Hsu, S.C., Kao, W.T., Lo, C.W., Lee, K.Y., Shao, J.S., Chen, Y.H., Chang, J., Chen, S.S. and Yu, M. J.* Phosphoproteomics identified an NS5A phosphorylation site involved in hepatitis C virus replication JOURNAL OF BIOLOGICAL CHEMISTRY 291(8), 3918-3931 (2016-02) [JCR] [WOS]
  4. Wong, M.T., and Chen, S.S.* Emerging roles of interferon-stimulated genes in innate immune response to hepatitis C virus infection. Cell. Mol. Immunol. 13(S1), 11-35 (2016-01) [JCR] [WOS]
  5. Klionsky D.J.*, and 2170 others (Chen, S.S. is an author) Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes Autophagy 12, 1-222 (2016-01) [JCR] [WOS]
  6. Ke, P.Y., and Chen, S.S.* Autophagy in hepatitis C virus-host interactions: potential roles and therapeutic targets for liver-associated diseases World Journal of Gastroenterology 20(19), 5773-5793 (2014-05) [JCR] [WOS]
  7. Chen, S.S.*, and Ke, P.Y. Suppression of innate antiviral immunity after hepatitis C virus infection: role of the unfolded protein response and autophagy (review) Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging Volume 2 - Role In General Diseases. Pages 137-159. Elsevier Publishing Company, London, UK (2014-01) [JCR] [WOS]
  8. Chen, S.S.*, and Ke, P.Y. Suppression of innate antiviral immunity after hepatitis C virus infection: role of the unfolded protein response and autophagy Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, and Infection. (Four-volume series) (2013-05-01) [JCR] [WOS]
  9. Ke, P.Y., and Chen, S.S.* Active RNA replication of hepatitis C virus downregulates CD81 expression PLoS One 8(1), e54866 (2013-01) [JCR] [WOS]
  10. Ke, P.Y., and Chen, S.S.* Multifaceted roles of autophagy in the life cycle of Flaviviridae Recent Research Developments in Virology-8th issue (2012-12) [JCR] [WOS]