Dr. Yang, Shi-Bing 's orcid link picture Dr. Yang, Shi-Bing 's publons link picture

Dr. Yang, Shi-Bing

Associate Research Fellow
  • 2652-3532 (Lab) (Room No: N701)

Specialty:
  • Neurophysiology
  • Energy Metabolism
  • Ion channels

Education and Positions:
  • Ph.D, University of Göttingen, Germany (Neuroscience)


Ion channels are membrane proteins that allow certain ions to rapidly cross the membrane. The orchestrated activities of ion channels generate various bioelectric phenomena, including nerve signal propagation, muscle contraction, and hormone release. Moreover, large-scale genetic analyses have identified ion channel mutations that are associated with human diseases. Combining patch-clamp recording with molecular and cell biology, our laboratory is interested in investigating the basic mechanisms that govern ion channel functions and exploring the roles of ion channels under physiological and pathological conditions. Currently, we are focusing on the ion channel mutations that are associated with diseases of the endocrine and nervous systems.

 

Journal 26 Book 1

  1. Athena H. Li, (Shi-Bing Yang)* The caveats and setbacks of mouse genome editing tools in biomedical studies gene reports 33, 101834 (2023-12) [JCR] [WOS]
  2. Athena H Li, (Shi-Bing Yang)* Utilizing Cre-lox-based mouse genetic tools in neuroscience research Gene Reports 33, 101825 (2023-12) [JCR] [WOS]
  3. Cheng-Ting Lee, Wen-Hao Tsai, Chien-Ching Chang, Pei-Chun Chen, Cathy Shen-Jang Fann, Hsueh-Kai Chang, Shih-Yao Liu, Mu-Zon Wu, Pao-Chin Chiu, Wen-Ming Hsu, Wei-Shiung Yang, Ling-Ping Lai, Wen-Yu Tsai, (Shi-Bing Yang)*, Pei-Lung Chen Genotype-phenotype correlation in Taiwanese children with diazoxide-unresponsive congenital hyperinsulinism FRONTIERS IN ENDOCRINOLOGY 14, 1283907 (2023-11) [JCR] [WOS]
  4. Hsu Hong-Ming, Yang Yen-Yu, Huang Yu-Hsin, Chu Chien-Hsin, Tu Ting-Jui, Wu Yen-Ting, Chiang Chu-Jen, (Yang Shi-Bing), Hsu Daniel K., Liu Fu-Tong, Tai Jung-Hsiang Distinct features of the host-parasite interactions between nonadherent and adherent Trichomonas vaginalis isolates PLOS Neglected Tropical Diseases 17(1), e0011016 (2023-01) [JCR] [WOS]
  5. Sandra Postić*, Marko Gosak, Wen-Hao Tsai, Johannes Pfabe, Srdjan Sarikas, Andraž Stožer, Dean Korošak, (Shi-Bing Yang) and Marjan Slak Rupnik pH-Dependence of Glucose-Dependent Activity of Beta Cell Networks in Acute Mouse Pancreatic Tissue Slice FRONTIERS IN ENDOCRINOLOGY 13, 916688 (2022-06-28) [JCR] [WOS]
  6. Wen-Hao Tsai, Cédric Grauffel, Ming-Yueh Huang, Sandra Postić, Marjan Slak Rupnik, Carmay Lim, (Shi-Bing Yang)* Allosteric coupling between transmembrane segment 4 and the selectivity filter of TALK1 potassium channels regulates their gating by extracellular pH JOURNAL OF BIOLOGICAL CHEMISTRY 298(6), 101998 (2022-06-01) [JCR] [WOS]
  7. Yuan-Hung Lin King, Chao Chen, John V. Lin King, Jeffrey Simms, Edward Glasscock, (Shi-Bing Yang), Yuh-Nung Jan, Lily Yeh Jan* Kv1.1 preserves the neural stem cell pool and facilitates neuron maturation during adult hippocampal neurogenesis PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 119(22), 2118240119 (2022-05-25) [JCR] [WOS]
  8. Ching-Han Lin, Yu-Chi Lin, (Shi-Bing Yang)*, Pei-Chun Chen Carbamazepine promotes surface expression of mutant Kir6. 2-A28V ATP-sensitive potassium channels by modulating Golgi retention and autophagy JOURNAL OF BIOLOGICAL CHEMISTRY 298(5), 101904 (2022-05-01) [JCR] [WOS]
  9. Wen-Ching Lin, Hao-Cheng Tang, Han Ying Wang, Chia-Yi Kao, You-Chiun Chang, Athena Hsu Li, (Shi-Bing Yang), and Kurt Yun Mou* Fragment-Directed Random Mutagenesis by the Reverse Kunkel Method ACS SYNTHETIC BIOLOGY 11(4), 1658-1668 (2022-03-24) [JCR] [WOS]
  10. Yu-Ju Chou*, Yu-Kai Ma, Yi-Han Lu, Jung-Tai King, Wen-Sheng Tasi, (Shi-Bing Yang)*, Tsung-Han Kuo* Potential cross-species correlations in social hierarchy and memory between mice and young children Communications Biology 5(230), 1-14 (2022-03-14) [JCR] [WOS]

- POSTDOC -
Tsai, Wen-Hao
Tsai, Wen-Hao
Li, Athena
Li, Athena
- RESEARCH ASSOCIATES -
Hsu, Yvonne
Hsu, Yvonne
Su, Amber
Su, Amber
member
Wu, Darron
- STUDENTS -
Lin, Shih-Che
Lin, Shih-Che
- ALUMNI -
Lu, Kuan-Ming
Lu, Kuan-Ming
Chou, Shu-Min
Chou, Shu-Min
Lee, Ming-Liang
Lee, Ming-Liang
Chen, Hui-Yu
Chen, Hui-Yu
Tsai, Hsin-Ju
Tsai, Hsin-Ju
Li, Su-Yi
Li, Su-Yi
member
Lee, Yi Heng