Dr. Chen, Yuan-Tsong 陳垣崇 博士



  • Two new susceptibility loci for Kawasaki disease identified through genome-wide association analysis.
    Nat Genet., May 25, 2012
    To find new candidate loci predisposing individuals to Kawasaki disease, an acute vasculitis that affects children, we conducted a genome-wi ......
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  • Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome.
    J Allergy Clin Immunol., Feb 07, 2012
    The endogenous peptide-loaded HLA-B∗1502 molecule presented CBZ to CTLs without the involvement of intracellular drug metabolism or a ......
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  • Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome.
    J Allergy Clin Immunol., Sep 14, 2011
    Stevens-Johnson syndrome (SJS) and its related disease, toxic epidermal necrolysis (TEN), are life-threatening drug hypersensitivities with ......
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  • Mitochondrial GLUT10 facilitates dehydroascorbic acid import and protects cells against oxidative stress: mechanistic insight into arterial tortuosity syndrome.
    Hum. Mol. Genet., Jul 24, 2010
    Mutations in glucose transporter 10 (GLUT10) alter angiogenesis and cause arterial tortuosity syndrome (ATS); however, the mechanisms by whi ......
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  • Mice with Alopecia, Osteoporosis, and Systemic Amyloidosis Due to Mutation in Zdhhc13, a Gene Coding for Palmitoyl Acyltransferase.
    PLoS Genet., Jun 10, 2010
    Protein palmitoylation has emerged as an important mechanism for regulating protein trafficking, stability, and protein–protein intera ......
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List of Highlights