Dr. Tang, Tang K. 唐堂 博士

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  • A novel HIF1α-STIL-FOXM1 axis regulates tumor metastasis
    Journal of Biomedical Science, Apr 01, 2022
        Background Metastasis is the major cause of morbidity and mortality in cancer that involves in multiple steps includi ......
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  • Modeling Human Primary Microcephaly With hiPSC-Derived Brain Organoids Carrying CPAP-E1235V Disease-Associated Mutant Protein
    Frontiers in Cell and Developmental Biology, Mar 02, 2022
          The centrosome is composed of a pair of centrioles and serves as the major microtubule-organizing center (MTOC ......
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  • CEP120-mediated KIAA0753 recruitment onto centrioles is required for timely neuronal differentiation and germinal zone exit in the developing cerebellum
    Genes & Development, Oct 28, 2021
        Joubert syndrome (JS) is a recessive ciliopathy in which all affected individuals have congenital cerebellar vermis hypo ......
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  • Human Microcephaly Protein RTTN Is Required for Proper Mitotic Progression and Correct Spindle Position
    Cells, Jun 09, 2021
        Autosomal recessive primary microcephaly (MCPH) is a complex neurodevelopmental disorder characterized by a small brain ......
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  • Loss of human microcephaly CPAP in developing mouse brain
    J Cell Sci, Jun 24, 2020
    Primary microcephaly (MCPH) is a neurodevelopmental disorder characterized by small brain size with mental retardation. CPAP/CENPJ, a known ......
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