Dr. Tarn, Woan-Yuh 's publons link picture

Dr. Tarn, Woan-Yuh

Distinguished Research Fellow
  • 02-27899015 (Lab) (Room No: N223)
  • 02-26523052
  • 02-27829142 (Fax)
Specialty:

 

  1. mRNA splicing in neuron
  2. translational control in cancer
  3. long non-coding RNA
Education and Positions:

  • Ph.D. National Tsing Hua University
    Postdoc Assoc. Yale University

Highlight Detail
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The RNA-binding protein Y14 inhibits mRNA decapping and modulates processing body formation.

Dr. Tarn, Woan-Yuh
Mol Biol Cell., Jan 01, 2013

The exon-junction complex (EJC) deposited on a newly spliced mRNA plays an important role in subsequent mRNA metabolic events. Here we show that an EJC core heterodimer, Y14/Magoh, specifically associates with mRNA-degradation factors, including the mRNA-decapping complex and exoribonucleases, whereas another core factor, eIF4AIII/MLN51, does not.

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