Dr. Tarn, Woan-Yuh
譚婉玉 博士
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Antisense Oligonucleotide-Based Therapy of Viral Infections
Pharmaceutics, Nov 26, 2021
Nucleic acid-based therapeutics have demonstrated their efficacy in the treatment of various diseases and vaccine develo ......
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The Y14-p53 regulatory circuit in megakaryocyte differentiation and thrombocytopenia
iScience, Nov 19, 2021
Thrombocytopenia-absent radius (TAR) syndrome is caused by RBM8A insufficiency. We generated megakaryocyte-specific  ......
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DDX3 modulates the tumor microenvironment via its role in endoplasmic reticulum-associated translation
iScience, Sep 24, 2021
Using antibody arrays, we found that the RNA helicase DDX3 modulates the expression of secreted signaling factors in ora ......
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p53 Activation in Genetic Disorders: Different Routes to the Same Destination
International journal of molecular sciences, Aug 27, 2021
The tumor suppressor p53 is critical for preventing neoplastic transformation and tumor progression. Inappropriate activ ......
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uORF-mediated translational control: recently elucidated mechanisms and implications in cancer
RNA Biology, Jun 24, 2019
Protein synthesis is tightly regulated, and its dysregulation can contribute to the pathology of various diseases, including cancer. Increas ......
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List of Highlights
文件紀錄
Antisense Oligonucleotide-Based Therapy of Viral Infections
Pharmaceutics Nov 26, 2021
The Y14-p53 regulatory circuit in megakaryocyte differentiation and thrombocytopenia
iScience Nov 19, 2021
DDX3 modulates the tumor microenvironment via its role in endoplasmic reticulum-associated translation
iScience Sep 24, 2021
p53 Activation in Genetic Disorders: Different Routes to the Same Destination
International journal of molecular sciences Aug 27, 2021
uORF-mediated translational control: recently elucidated mechanisms and implications in cancer
RNA Biology Jun 24, 2019
The RNA Processing Factor Y14 Participates in DNA Damage Response and Repair
iScience Mar 21, 2019
Interference of DNAJB6/MRJ Isoform Switch by Morpholino Inhibits Replication of HIV-1 and RSV
Molecular Therapy-Nucleic Acids Dec 10, 2018
DDX3 activates CBC-eIF3-mediated translation of uORF-containing oncogenic mRNAs to promote metastasis in HNSCC
Cancer research Jun 19, 2018
RBM4 modulates radial migration via alternative splicing of Dab1 during cortex development
Molecular and cellular biology Mar 26, 2018
Y14 governs p53 expression and modulates DNA damage sensitivity
Scientific Reports Mar 31, 2017
RBM4 regulates neuronal differentiation of mesenchymal stem cells by modulating alternative splicing of pyruvate kinase M
Molecular and Cellular Biology Nov 07, 2016
DDX3 modulates dendrite outgrowth and dendritic spine formation via PKA–Rac1 signaling in primary hippocampal neurons.
The Journal of Neuroscience Sep 21, 2016
RBM4 promotes neuronal differentiation and neurite outgrowth by modulating Numb isoform expression
Molecular Biology of the Cell May 15, 2016
DDX3 regulates the Rac1-β-catenin signaling pathway.
Oncogene May 21, 2015
Alanine repeats influence protein localization in splicing speckles and paraspeckles.
Nucleic Acids Res. Nov 20, 2014
TRAP150 activates splicing in composite terminal exons.
Nucl. Acids Res. Oct 17, 2014
DDX3 modulates cell adhesion and motility and cancer cell metastasis via Rac1-mediated signaling pathway.
Oncogene. Jul 21, 2014
RBM4 Promotes Pancreas Cell Differentiation and Insulin Expression.
Mol Cell Biol. Jan 13, 2013
The RNA-binding protein Y14 inhibits mRNA decapping and modulates processing body formation.
Mol Biol Cell. Jan 01, 2013
hnRNP Q regulates Cdc42-mediated neuronal morphogenesis.
Mol Cell Biol. Apr 09, 2012
RBM4 down-regulates PTB and antagonizes its activity in muscle cell–specific alternative splicing.
JCB. May 02, 2011
DDX3 regulates cell growth through translational control of cyclin E1 .
Mol. Cell. Biol. Sep 13, 2010
TRAP150 activates pre-mRNA splicing and promotes nuclear mRNA degradation
Nucleic Acids Research Jan 31, 2010
A role for transportin in deposition of TTP to cytoplasmic RNA granules and mRNA decay.
Nucl Acids Res. Sep 03, 2009
The RNA binding protein hnRNP Q modulates the utilization of exon 7 in the survival motor neuron 2 (
SMN2
) gene.
MCB. Sep 15, 2008
The DEAD-box RNA Helicase DDX3 Associates with Export mRNPs as well as TAP and Participates in Translational Control.
Mol Biol Cell. Jul 02, 2008
Cell stress modulates the function of splicing regulatory protein RBM4 in translation control.
Proc Natl Acad Sci USA. Feb 06, 2007
Alternative splicing and bioinformatic analysis of human U12-type introns
Nucleic Acids Research. Jan 04, 2007
Exon Selection in
a
-Tropomyosin mRNA Is Regulated by the Antagonistic Action of RBM4 and PTB.
Molecular and Cellular Biology Nov 01, 2005
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