Dr. Lin, Yi-Ling
Distinguished Research Fellow
Division Chief
- 02-2789-9013 (Lab) (Room No: 443)
- 02-2652-3902
- 02-2785-8847 (Fax)
-
Specialty:
- Molecular Virology
- Viral Pathogenesis
- Viral Immunology
Education and Positions:
1992, PhD, University of California, Los Angeles (UCLA), USA
2020 ~ date, CEO, Emerging Infectious Disease Division (EIDD), Biomedical Translation Research Center (BioTReC), Academia Sinica
Contact Information:
Highlight Detail
Drug Repurposing of Prochlorperazine Against Dengue Virus Infection.
Dr. Lin, Yi-Ling
J Infect Dis., Jul 14, 2014The increasing prevalence of dengue virus (DENV) infection presents serious disease and economic burden in epidemic countries. Despite the clinical importance, no DENV vaccine or anti-DENV drug is available. In this study, we found that prochlorperazine (PCZ), a dopamine D2 receptor (D2R) antagonist approved to treat nausea, vomiting and headache in humans, has potent in vitro and in vivo antiviral activity against DENV infection.