Dr. Tao, Mi-Hua 陶秘華 博士

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重要成果

  • Combination of radiation and interleukin 12 eradicates large orthotopic hepatocellular carcinoma through immunomodulation of tumor microenvironment
    OncoImmunology, Jul 23, 2018
    Immunotherapies have shown promising results in certain cancer patients. For hepatocellular carcinoma (HCC), the multiplicity of an immunoto ......
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  • Combinatorial RNA Interference Therapy Prevents Selection of Preexisting HBV Variants in Human Liver Chimeric Mice.
    Scientific Reports, Oct 20, 2015
    Selection of escape mutants with mutations within the target sequence could abolish the antiviral RNA interference activity. Here, we inv ......
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  • Studies of Efficacy and Liver Toxicity Related to Adeno-associated Virus-mediated RNA Interference.
    Human Gene Therapy, Aug 01, 2013
    Adeno-associated virus (AAV)-mediated RNA interference shows promise as a therapy for chronic hepatitis B virus (HBV) infection, but its ......
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  • Cancer Immunotherapy Using a Membrane-bound Interleukin-12 With B7-1 Transmembrane and Cytoplasmic Domains.
    Molecular Therapy, Feb 14, 2012
    Interleukin-12 (IL-12) has potent antitumor activity, but its clinical application is limited by severe systemic toxicity, which might be al ......
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  • Hydrogel-delivered GM-CSF Overcomes Nonresponsiveness to Hepatitis B Vaccine Through The Recruitment and Activation of Dendritic Cells.
    Journal of Immunology., Nov 01, 2010
    The standard hepatitis B surface Ag (HBsAg) vaccine fails to induce anti-hepatitis B surface Abs in 5-10% of healthy subjects, a phenomen ......
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