Dr. Chau, Lee-Young 趙麗洋 博士

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  • Siglec-E retards atherosclerosis by inhibiting CD36-mediated foam cell formation
    Journal of Biomedical Science, Jan 05, 2021
    Abstract Background The accumulation of lipid-laden macrophages, foam cells, within sub-endothelial intima is a key feature of early a ......
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  • Gal-1 (Galectin-1) Upregulation Contributes to Abdominal Aortic Aneurysm Progression by Enhancing Vascular Inflammation
    Arteriosclerosis, Thrombosis, and Vascular Biology, Nov 05, 2020
    Abstract Objective: Abdominal aortic aneurysm (AAA) is a vascular degenerative disease causing sudden rupture of aorta and signi ......
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  • Signal peptide peptidase promotes tumor progression via facilitating FKBP8 degradation
    Oncogene, Oct 22, 2018
    Signal peptide peptidase (SPP) is an endoplasmic reticulum (ER)-resident aspartyl protease mediating intramembrane cleavage of type II trans ......
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  • Galectin-1 Restricts Vascular Smooth Muscle Cell Motility Via Modulating Adhesion Force and Focal Adhesion Dynamics
    Scientific Reports, Jul 31, 2018
    Vascular smooth muscle cell (VSMC) migration play a key role in the development of intimal hyperplasia and atherosclerosis. Galectin-1 (Gal- ......
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  • Acetylation is essential for nuclear heme oxygenase-1-enhanced tumor growth and invasiveness
    Oncogene, Aug 28, 2017
    Overexpression of heme oxygenase-1 (HO-1), an endoplasmic reticulum-anchored enzyme, is observed in many cancers. HO-1 nuclear translocation ......
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