Dr. Chen, Chien-Chang ’s Lab陳建璋 博士 實驗室

Early Growth Response 1 is an Early Signal Inducing Cav3.2 T-type Calcium Channels During Cardiac Hypertrophy.

The Ca_v3.2 T-channel plays a pivotal role in inducing calcineurin/nuclear factor of activated T cell (NFAT) signaling during cardiac hypertrophy. Because calcineurin/NFAT signaling is induced early after pressure overload, we hypothesized that Ca_v3.2 is induced by an early signal.