Dr. Chen, Chien-Chang
Research Fellow
- 02-2652-3944 (Lab) (Room No: N713)
- 02-2652-3522 (Office)
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Specialty:
- Chronic Pain
- Calcium Channel
- Cardiovascular Disease
Education and Positions:
Ph.D., University of Illinois, Urbana-Champaign
Highlight Detail
The CaV3.2 T-Type Ca2+ Channel Is Required for Pressure Overload–Induced Cardiac Hypertrophy in Mice.
Dr. Chen, Chien-Chang
Circulation Research., Jan 02, 2009Voltage-gated T-type Ca2+ channels (T-channels) are normally expressed during embryonic development in ventricular myocytes but are undetectable in adult ventricular myocytes. Interestingly, T-channels are reexpressed in hypertrophied or failing hearts. It is unclear whether T-channels play a role in the pathogenesis of cardiomyopathy and what the mechanism might be.Here we show that the a1H voltage-gated T-type Ca2+ channel (Cav3.2) is involved...