Dr. Fann, Cathy S.-J.
Research Fellow
- 02-27899144 (Lab) (Room No: 100)
- 02-27823047 (Fax)
-
Specialty:
- Genetic Statistics
- Genetic Epidemiology
Education and Positions:
Division of Biostatistics, Department of Preventive Medicine and Environmental Health,
Ph.D. University of Iowa, Iowa City, Iowa, US
Highlight Detail
Genetic determinants of antithyroid drug-induced agranulocytosis by human leukocyte antigen genotyping and genome-wide association study.
Dr. Fann, Cathy S.-J.
Nat Commun., Jul 07, 2015Graves' disease is the leading cause of hyperthyroidism affecting 1.0-1.6% of the population. Antithyroid drugs are the treatment cornerstone, but may cause life-threatening agranulocytosis. Here we conduct a two-stage association study on two separate subject sets (in total 42 agranulocytosis cases and 1,208 Graves' disease controls), using direct human leukocyte antigen genotyping and SNP-based genome-wide association study.