Dr. Yang, Ruey-Bing (Ray)楊瑞彬 博士

List of Highlights
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• Signal peptide-CUB-EGF-like repeat-containing protein 1-promoted FLT3 signaling is critical for the initiation and maintenance of MLL-rearranged acute leukemia

  Haematologica Aug 25, 2022

• Plasma Galectin-9 Is a Useful Biomarker for Predicting Renal Function in Patients Undergoing Native Kidney Biopsy

  Archives of pathology & laboratory medicine Jun 10, 2022

• Urinary Galectin-3 as a Novel Biomarker for the Prediction of Renal Fibrosis and Kidney Disease Progression

  Biomedicines Mar 02, 2022

• Quantitative glycoproteomics analysis identifies novel FUT8 targets and signaling networks critical for breast cancer cell invasiveness

  Breast Cancer Research Mar 18, 2022

• Zebrafish scube1 and scube2 cooperate in promoting Vegfa signaling during embryonic vascularization

  Cardiovascular Research Mar 31, 2021

• SCUBE3 loss-of-function causes a recognizable recessive developmental disorder due to defective bone morphogenetic protein signaling

  American Journal of Human Genetics Dec 11, 2020

• Epidermal growth factor-like repeats of SCUBE1 derived from platelets are critical for thrombus formation

  Cardiovascular Research Feb 05, 2019

• SCUBE1-enhanced bone morphogenetic protein signaling protects against renal ischemia-reperfusion injury

  Biochimica et biophysica acta: molecular basis of disease Nov 07, 2018

• Inhibition of Endothelial SCUBE2 (Signal Peptide-CUB-EGF Domain-Containing Protein 2), a Novel VEGFR2 (Vascular Endothelial Growth Factor Receptor 2) Coreceptor, Suppresses Tumor Angiogenesis

  Arteriosclerosis, Thrombosis, and Vascular Biology Mar 15, 2018

• FUT8 promotes breast cancer cell invasiveness by remodeling TGF-β receptor core fucosylation

  Breast Cancer Research Oct 05, 2017

• Guanylyl cyclase‐G is an alarm pheromone receptor in mice

  EMBO Journal Sep 28, 2017

• Endothelial SCUBE2 Interacts With VEGFR2 and Regulates VEGF-Induced Angiogenesis

  Arteriosclerosis, Thrombosis, and Vascular Biology Nov 10, 2016

• Disruption of Scube2 impairs endochondral bone formation.

  J. Bone Miner. Res. Jan 12, 2015

• Receptor guanylyl cyclase‐G is a novel thermosensory protein activated by cool temperatures.

  EMBO J. Dec 01, 2014

• SCUBE3 (Signal Peptide-CUB-EGF Domain-containing Protein 3) Modulates Fibroblast Growth Factor Signaling during Fast Muscle Development.

  JBC. May 21, 2014

• Inhibition of the Plasma SCUBE1, a Novel Platelet Adhesive Protein, Protects Mice Against Thrombosis.

  Arterioscler Thromb Vasc Biol. May 15, 2014

• Tumor suppressor SCUBE2 inhibits breast-cancer cell migration and invasion through the reversal of epithelial-mesenchymal transition

  J Cell Sci. Nov 08, 2013

• Zebrafish scube1 (Signal Peptide-CUB (Complement Protein C1r/C1s, Uegf, and Bmp1)-EGF (Epidermal Growth Factor) Domain-containing Protein 1) Is Involved in Primitive Hematopoiesis.

  J Biol Chem. Feb 15, 2013

• ATF3-Mediated Epigenetic Regulation Protects against Acute Kidney Injury.

  JASN Apr 01, 2010

• Receptor guanylyl cyclases in Inka cells targeted by eclosion hormone.

  PNAS Jul 28, 2009

• SCUBE2 Suppresses Breast Tumor Cell Proliferation and Confers a Favorable Prognosis in Invasive Breast Cancer.

  Cancer Research Apr 15, 2009

• Plasma concentration of SCUBE1, a novel platelet protein, is elevated in patients with acute coronary syndrome and ischemic stroke.

  J. Am Coll Cardiol. Jun 03, 2008

• Disruption of Guanylyl Cyclase-G Protects against Acute Renal Injury.

  J. of the Am. Soc. of Nephrology. Jan 16, 2008