Structural insights into DNA binding domain of vancomycin-resistance-associated response regulator in complex with its promoter DNA from Staphylococcus aureus
Protein Science, Apr 09, 2022
In Staphylococcus aureus, vancomycin-resistance-associated response regulator (VraR) is a part of the Vra ......
Protein–DNA complex-guided discovery of the antibacterial lead E1 for restoring the susceptibility of Klebsiella Pneumoniae to polymyxin B by targeting the response regulator PmrA
Chemical Communications, May 24, 2018
A new antibacterial drug is urgently needed. We employed a protein–DNA complex-guided pharmacophore modeling approach to screen inhibi ......